IP Library Granted Patent US 8,668,727
Granted Patent B2
US 8,668,727 · App. 13/592,883 · Granted Mar 11, 2014

Systems and methods for treating pathogenic infection

Inventors: Anthony Natale (New Preston, CT); David Muller (Boston, MA)
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Quick Facts
Patent No.
US 8,668,727
App. No.
13/592,883
Granted
Mar 11, 2014
Kind
B2
Abstract

An internal anatomic target that is infected by pathogenic microorganisms is treated using an applicator configured for delivering a therapeutic solution thereto and an UV light-emitting device transmits UV light thereon.

Claims (15)

1. A system for treating pathogenic infections comprising:

a UV light-emitting device having an emission output;

an applicator integrated therewith, the applicator comprising a fluid reservoir for containing a riboflavin solution and a fluid outlet, wherein the emission output and the fluid outlet are configured for accessing an internal anatomical target and delivering the riboflavin solution and UV light thereto;

an actuator and a forcing mechanism, the actuator being remotely actuable by a user and configured to (i) cause the forcing mechanism to force the riboflavin solution from the fluid reservoir through the fluid outlet and (ii) cause the light-emitting device to emit UV light through the emission output; and

an inflatable balloon proximal to the fluid outlet;

wherein the actuator is a mechanical, electrical or electromechanical actuator and the applicator is configured to deliver the riboflavin solution through the fluid outlet with the balloon inflated to form a proximal dam preventing dispersal of the fluid.

2. The system of claim 1 , wherein the actuator comprises a handle and a guide wire.

3. The system of claim 1 , further comprising a user interface for electronically operating the actuator.

4. The system of claim 3 , wherein the user interface communicates wirelessly with the actuator.

5. The system of claim 4 , wherein the user interface is a smartphone, a tablet, or a computer.

6. The system of claim 4 , wherein the user interface receives and displays feedback information from the actuator.

7. The system of claim 1 , wherein the emission output and the fluid outlet are formed into a delivery component that is flexible or articulated with an alterable shape to facilitate access to different internal anatomical targets.

8. The system of claim 1 , further comprising a surgical instrument integrated with the system in a single structure.

9. The system of claim 1 , further comprising at least one optical fiber for conducting light from the UV light-emitting device to the emission output.

10. The system of claim 1 , wherein the actuator is further configured to alternately operate the balloon and the forcing mechanism.

Continuity (2)
Provisional Application 61526346 · Aug 23, 2011
Related Publication 20130072852A1 · Mar 21, 2013