4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
View Patent ↗The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
1. A method for treating a condition selected from the group consisting of diabetes, cardiovascular diseases, Metabolic X Syndrome, hypercholesterolemia, hypo-HDL-cholesterolemia, hyper-LDL-cholesterolemia, dyslipidemia, atherosclerosis, and obesity comprising administering to a patient in need of such treatment an effective amount of a compound having the following structure
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 , wherein the condition is diabetes.
3. The method of claim 1 , wherein the condition is cardiovascular diseases.
4. The method of claim 1 , wherein the condition is Metabolic X Syndrome.
5. The method of claim 1 , wherein the condition is hypercholesterolemia.
6. The method of claim 1 , wherein the condition is hypo-HDL-cholesterolemia.
7. The method of claim 1 , wherein the condition is hyper-LDL-cholesterolemia.
8. The method of claim 1 , wherein the condition is dyslipidemia.
9. The method of claim 1 , wherein the condition is atherosclerosis.
10. The method of claim 1 , wherein the condition is obesity.