Fluid drainage device, delivery device, and associated methods of use and manufacture

1. An intraocular implant for allowing fluid flow from the anterior chamber of an eye, comprising:

a tube having an inlet end, an outlet end, and a tube passage;

wherein the inlet end is adapted to extend into the anterior chamber of the eye;

wherein the outlet end is adapted to be implanted adjacent scleral tissue of the eye; and

wherein the implant is adapted to drain aqueous humor into a suprachoroidal space or into a juxta-uveal space; and

wherein the implant further comprises a flange at the inlet end or the outlet end, wherein the flange has one or more grooves or access pockets configured to receive the wall of a delivery device such that the wall of the delivery device is positioned between the flange of the implant and the tube of the implant.

2. An intraocular implant according to claim 1 , further comprising one or more flat surfaces along the length of the tube, giving the tube a reduced profile.

3. An intraocular implant according to claim 1 , wherein an angle between the tube and a surface of the flange is about 10 to about 30 degrees.

4. An intraocular implant according to claim 1 , wherein the tube has one or more narrow areas, reduced profiles, or holes for suturing the implant in position.

5. A delivery device in combination with an intraocular implant for allowing fluid flow from the anterior chamber of an eye,

wherein the implant comprises a tube having an inlet end, an outlet end, and a tube passage;

wherein the inlet end is adapted to extend into the anterior chamber of the eye;

wherein the outlet end is adapted to be implanted adjacent scleral tissue of the eye to drain aqueous humor into a suprachoroidal space or into a juxta-uveal space;

wherein the implant further comprises a flange at the inlet end or the outlet end, wherein the flange has one or more grooves or access pockets;

wherein the delivery device comprises a rodlike instrument; and

wherein the delivery device comprises a bore for accommodating the implant and a wall that is adapted to be received by the one or more grooves or access pockets in the flange of the implant such that the wall of the delivery device is positioned between the flange of the implant and the tube of the implant.

6. A method of implanting an intraocular implant, comprising:

providing an implant comprising a tube having an inlet end, an outlet end, and a tube passage;

wherein the inlet end is adapted to extend into the anterior chamber of the eye;

wherein the outlet end is adapted to be implanted adjacent scleral tissue of the eye;

wherein the implant further comprises a flange at the inlet end or the outlet end, wherein the flange has one or more grooves or access pockets;

providing a delivery device comprising a rodlike instrument;

wherein the delivery device comprises a bore for accommodating the implant and a wall that is adapted to be received by the one or more grooves or access pockets in the flange of the implant;

loading the implant in or on the delivery device, with the wall of the delivery device being received by the one or more grooves or access pockets in the flange of the implant such that the wall of the delivery device is positioned between the flange of the implant and the tube of the implant;

forming an incision in the eye;

directing the implant to a desired implantation location, wherein the implant is positioned to drain aqueous humor into a suprachoroidal space or into a juxta-uveal space; and

withdrawing the delivery device.

7. A method according to claim 6 , wherein the implantation is performed ab externo.

8. A method according to claim 6 , wherein the implantation is performed ab intern.

9. A method according to claim 6 , wherein the outlet end of the implant is implanted in a suprachoroidal location.

10. A method according to claim 6 , wherein the outlet end of the implant is implanted in a juxta-uveal location.