IP Library Granted Patent US 9,275,191
Granted Patent B2
US 9,275,191 · App. 13/616,007 · Granted Mar 1, 2016

Methods and systems for producing an implant

Inventors: H. David Dean (Shaker Heights, OH); Krishnamoorthy Subramanyan (Palatine, IL); Alexandros T. Moullas (Thessaloniki, GR); Robert A. Ratcheson (Shaker Heights, OH)
Assignee: Osteoplastics LLC
G06F19/3437A61F2/30942G06F19/321G06F19/3481G06K9/34G06K9/6251G06T7/0014G06T17/00A61B6/505A61F2/28A61F2002/2835G06K2209/05G06T2207/30008
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Quick Facts
Patent No.
US 9,275,191
App. No.
13/616,007
Granted
Mar 1, 2016
Kind
B2
Abstract

A computer implemented method for determining the 3-dimensional shape of an implant to be implanted into a subject includes obtaining a computer readable image including a defective portion and a non-defective portion of tissue in the subject, superimposing on the image a shape to span the defective portion, and determining the 3-dimensional shape of the implant based on the shape that spans the defective portion.

Claims (24)

1. A method for fabricating a 3-dimensional implant to be implanted into a subject, the method comprising:

obtaining a computer readable image including a defective portion and a non-defective portion of tissue in the subject;

identifying anatomical landmarks on the image;

superimposing on the image a 3-dimensional template to span the defective portion;

deforming the template to match the anatomical landmarks on the image;

determining a 3-dimensional shape of the implant based on the template that spans the defective portion; and

fabricating the implant having the 3-dimensional shape.

2. The method of claim 1 , wherein the superimposing on the image the template to span the defective portion includes:

mapping highly curved portions of surfaces of at least one of:

the subject and another individual, or

the subject and an average, wherein the average comprises an average of the surfaces of more than one individual and

establishing correspondence between the mapped highly curved portions.

3. The method as set forth in claim 1 , wherein the computer readable image consists of slices of the defective portion and the non-defective portion.

4. The method as set forth in claim 1 , wherein the computer readable image consists of scan lines of the defective portion and the non-defective portion.

5. The method as set forth in claim 1 , wherein the computer readable image consists of voxels of the defective portion and the non-defective portion.

6. The method as set forth in claim 1 , further including:

determining a position for optimal adjacency between the implant and the non-defective portion of the subject.

7. The method as set forth in claim 1 , wherein the template that spans the defective portion in the subject represents an average shape of corresponding normal tissue in the patient.

8. The method as set forth in claim 1 , wherein fabricating the implant comprises printing with a 3-dimensional rendering device.

9. The method as set forth in claim 1 , wherein the template that spans the defective portion is drawn on the image as the image is displayed by a computer.

10. The method as set forth in claim 9 , wherein the template that spans the defective portion represents a right-left mirror image of a portion of the subject's anatomy that includes the defective portion.

11. The method of claim 10 , wherein determining the 3-dimensional shape of the implant is determined as a function of respective shapes of the defective portion and the template.

12. The method as set forth in claim 1 , wherein the template that spans the defective portion in the subject represents corresponding normal tissue in at least one other individual.

13. The method as set forth in claim 12 , wherein the determining the 3-dimensional shape of the implant is determined as a function of respective shapes of the defective portion and the template.

Assignments (11)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2018
From: DEAN, H. DAVID; SUBRAMANYAN, KRISHNAMOORTHY; MOULLAS, ALEXANDROS T.; RATCHESON, ROBERT A.
To: CASE WESTERN RESERVE UNIVERSITY
Reel/Frame 046489/0922 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2018
From: CASE WESTERN RESERVE UNIVERSITY
To: DEAN, HOWARD DAVID; RATCHESON, ROBERT; SUBRAMANYAN, KRISHNAMOORTHY; MOULLAS, ALEXANDROS TH.
Reel/Frame 046489/0958 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2018
From: DEAN, HOWARD DAVID
To: OSTEOPLASTICS, LLC
Reel/Frame 046490/0005 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2018
From: RATCHESON, ROBERT
To: OSTEOPLASTICS, LLC
Reel/Frame 046490/0013 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2018
From: SUBRAMANYAN, KRISHNAMOORTHY
To: OSTEOPLASTICS, LLC
Reel/Frame 046490/0030 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2018
From: MOULLAS, ALEXANDROS TH.
To: OSTEOPLASTICS, LLC
Reel/Frame 046490/0053 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 14, 2017
From: MOULLAS, ALEXANDROS TH.
To: OSTEOPLASTICS, LLC
Reel/Frame 041250/0477 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2015
From: RATCHESON, ROBERT
To: OSTEOPLASTICS, LLC
Reel/Frame 035822/0021 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2015
From: SUBRAMANYAN, KRISHNAMOORTHY
To: OSTEOPLASTICS, LLC
Reel/Frame 035814/0549 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 12, 2015
From: DEAN, HOWARD DAVID
To: OSTEOPLASTICS LLC
Reel/Frame 035616/0541 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 17, 2013
From: DEAN, HOWARD DAVID; MOULLAS, ALEXANDROS TH.; RATCHESON, ROBERT; SUBRAMANYAN, KRISHNAMOORTHY
To: OSTEOPLASTICS LLC
Reel/Frame 031433/0809 →
Continuity (6)
Continuation 13228517 · Sep 9, 2011
Continuation 10089467
Provisional Application 60148393 · Aug 11, 1999
Provisional Application 60148275 · Aug 11, 1999
Provisional Application 60148277 · Aug 11, 1999
Related Publication 20130018497A1 · Jan 17, 2013