Method of treating vitamin B
View Patent ↗A novel method and composition for treating vitamin B 12 deficiency mammals that fail to respond to oral vitamin B 12 therapy.
1. A tablet comprising (a) about 0.1 to about 20 mg of vitamin B 12 ; and (b) about 10 to about 200 mg of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate.
2. The tablet of claim 1 , wherein the tablet comprises about 0.5 to about 10 mg of vitamin B 12 .
3. The tablet of claim 1 , further comprising from about 0.5 to about 10 mg of povidone.
4. The tablet of claim 1 , further comprising from about 1 to about 8 mg of povidone.
5. The tablet of claim 1 , further comprising from about 1.5 to about 5 mg of povidone.
6. The tablet of claim 1 , wherein the vitamin B 12 is cyanocobalamin.
7. A tablet comprising (a) about 0.1 to about 1.5 mg of vitamin B 12 ; and (b) about 25 to about 150 mg of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate.
8. The tablet of claim 7 , further comprising from about 0.5 to about 10 mg of povidone.
9. The tablet of claim 7 , further comprising from about 1 to about 8 mg of povidone.
10. The tablet of claim 7 , further comprising from about 1.5 to about 5 mg of povidone.
11. The tablet of claim 7 , wherein the vitamin B 12 is cyanocobalamin.
12. A method of treating vitamin B 12 deficiency in a human subject in need thereof comprising orally administering the tablet of claim 1 .
13. A method of treating vitamin B 12 deficiency in a human subject in need thereof comprising orally administering the tablet of claim 7 .
14. The method of claim 12 , wherein said subject had failed to respond to existing oral vitamin B 12 treatment.
15. The method of claim 13 , wherein said subject had failed to respond to existing oral vitamin B 12 treatment.