In-vitro contact lens testing

1. A device comprising:

a housing configured to hold one or more contact lenses; and

a testing component disposed within the housing that is configured to test for presence of one or more biomarkers bound to one or more receptors disposed in one or more cavities formed at predetermined locations within a body of a contact lens placed within the testing component and to facilitate determining state information associated with a state of an individual from which the biomarkers were generated, wherein the one or more cavities have openings on an inner surface or outer surface of the contact lens and have depths less than a thickness of the contact lens.

2. The device of claim 1 , wherein the one or more biomarkers bound to the one or more receptors are located in tear fluid generated by the individual and held within the one or more cavities.

3. The device of claim 2 , further comprising, an extraction component disposed within the housing and configured to extract the tear fluid comprising the one or more biomarkers bound to one or more receptors disposed in the one or more cavities without disrupting bonds between the one or more biomarkers and the one or more receptors.

4. The device of claim 1 , the testing component further comprising:

a rinsing compartment comprising a rinsing solution and configured to remove at least one of unbound biomarkers or unbound receptors from the contact lens when the contact lens is provided therein.

5. The device of claim 1 , the testing component further comprising:

a detection compartment comprising detector molecules configured to bind to the one or more receptors having the one or more biomarkers bound thereto and produce a signal in response to binding when the contact lens is placed within the detection compartment.

6. The device of claim 1 , the testing component further comprising:

a detection compartment comprising detector molecules configured to bind to the one or biomarkers bound to the one more receptors and produce a signal in response to binding when the contact lens is placed within the detection compartment.

7. The device of claim 6 , wherein the detector molecules include first detector molecules comprising a detector antibody covalently linked to an enzyme, the detector antibody configured to bind to the one or biomarkers bound to the one or more receptors, and second detector molecules comprising a substrate configured to bind to the enzyme to produce the signal.

8. The device of claim 7 , the testing component further comprising:

a first detection compartment comprising first detector molecules;

a second detection compartment comprising second detector molecules; and

a rinsing compartment comprising a rinsing solution that removes unbound biomarkers and unbound first detector molecules from the contact lens when the contact lens is provided therein.

9. The device of claim 1 , wherein the state information includes at least one of a glucose level, alcohol level, histamine level, urea level, lactate level, cholesterol level, sodium ion level, potassium ion level, calcium ion level or magnesium ion level of the individual.

10. The device of claim 1 , further comprising:

a control component configured to control testing carried out in the device.

11. The device of claim 1 , wherein the one or more receptors include a first receptor and a second receptor, wherein the one or more cavities include a first cavity and a second cavity, and wherein the first receptor is disposed in the first cavity and the second receptor is disposed in the second cavity.

12. The device of claim 1 , wherein the one or more cavities include a first cavity having an opening on the inner surface of the contact lens and a second cavity having an opening on the outer surface of the contact lens.