COMPOSITION CONTAINING REDUCED COENZYME Q10, AND MANUFACTURING AND STABILISING METHODS THEREFOR
The present invention relates to a method of producing reduced coenzyme Q10, including reducing oxidized coenzyme Q10 using a reducing agent in terpenes that can highly dissolve oxidized coenzyme Q10 and reduced coenzyme Q10 in the co-existence of at least one kind of additive selected from the group consisting of alcohols, water, a surfactant and diacylglycerol. In addition, the present invention relates to a composition comprising terpenes, a reducing agent, reduced coenzyme Q10 and at least one kind selected from the group consisting of alcohols, water, a surfactant and diacylglycerol, and a method of stabilizing reduced coenzyme Q10 comprising preparing the composition.
1 . A method of producing reduced coenzyme Q10 comprising, reducing oxidized coenzyme Q10 with a reducing agent in terpenes in the co-existence of at least one kind of additive selected from the group consisting of alcohols, water, a surfactant and diacylglycerol.
2 . The production method according to claim 1 , wherein the alcohol is a monovalent alcohol having 1 to 4 carbon atoms or a divalent alcohol having 2 to 4 carbon atoms.
3 . (canceled)
4 . (canceled)
5 . The production method according to claim 1 , wherein the terpene is at least one selected from the group consisting of hemiterpene, monoterpene, sesquiterpene, diterpene, sesterterpene and triterpene.
6 . The production method according to claim 1 , wherein the reducing agent is at least one selected from the group consisting of L-ascorbic acid, D-arabo-ascorbic acid, L-ascorbylpalmitate, L-ascorbylstearate, sodium borohydride, sodium hydrosulfite, retinal, an acerola extract, a pine bark extract, a KOKIYO extract, a gardenia pigment and a KOZU (fragrant vineger).
7 . The production method according to claim 1 , wherein the reduction reaction is performed in co-existence with fats, oils or mixtures thereof
8 . (canceled)
9 . The production method according to claim 1 , wherein the concentration of oxidized coenzyme Q10 is 0.001 wt % or more relative to total amount of the reaction mixture at the time of the start of the reduction reaction.
10 . The production method according to claim 1 , wherein the reduction reaction is performed in a preparation.
11 . The production method according to claim 10 , wherein the preparation is a capsule.
12 . The production method according to claim 11 , wherein the capsule is a soft capsule.
13 . The production method according to claim 1 , wherein the reduction reaction is performed under a deoxygenated atmosphere.
14 . A composition containing terpenes, a reducing agent, reduced coenzyme Q10 and at least one kind selected from the group consisting of alcohols, water, a surfactant and diacylglycerol.
15 . The composition according to claim 14 , wherein the alcohol is a monovalent alcohol having 1 to 4 carbon atoms or a divalent alcohol having 2 to 4 carbon atoms.
16 . (canceled)
17 . The composition according to claim 14 , wherein the terpene is at least one selected from the group consisting of hemiterpene, monoterpene, sesquiterpene, diterpene, sesterterpene and triterpene.
18 . The composition according to claim 14 , wherein the reducing agent is at least one selected from the group consisting of L-ascorbic acid, D-arabo-ascorbic acid, L-ascorbylpalmitate, L-ascorbylstearate, sodium borohydride, sodium hydrosulfite, retinal, an acerola extract, a pine bark extract, a KOKIYO extract, a gardenia pigment and a KOZU (fragrant vineger).
19 . The composition according to claim 14 , further comprising fats, oils or mixtures thereof.
20 . The composition according to claim 14 , wherein the content of reduced coenzyme Q10 in the composition is 0.001 wt % or more.
21 . The composition according to claim 14 , wherein the reduced coenzyme Q10 is added from the outside.
22 . The composition according to claim 14 , wherein the reduced coenzyme Q10 is reduced in the composition.
23 . A method of stabilizing reduced coenzyme Q10, comprising placing terpenes, a reducing agent and at least one kind selected from the group consisting of alcohols, water, a surfactant and diacylglycerol in co-existence.
24 . (canceled)
25 . (canceled)
26 . (canceled)
27 . (canceled)
28 . (canceled)
29 . (canceled)
30 . (canceled)