HERBAL COMPOSITION PHY906 AND ITS USE IN CHEMOTHERAPY
This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy.
1 - 17 . (canceled)
18 . A method of treating cancer in a mammal comprising co-administering a therapeutically effective amount of
i) an herbal preparation consisting essentially of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora ; and
ii) a chemotherapeutic formulation comprising a chemotherapeutic compound.
19 . The method of claim 18 , wherein the herbal preparation is administered via oral route, and the chemotherapeutic formulation is administered via oral or parenteral route.
20 . The method of claim 19 , wherein the herbal preparation is administered via oral route, and the chemotherapeutic formulation is administered via intravenous route.
21 . The method of claim 18 , wherein the herbal preparation consists of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora , and one or more pharmaceutically acceptable carriers.
22 . The method of claim 18 , wherein the herbal preparation is administered before the administration of the chemotherapeutic formulation.
23 . The method of claim 18 , wherein the herbal preparation is administered after the administration of the chemotherapeutic formulation.
24 . The method of claim 18 , wherein the herbal preparation is administered concurrently with the administration of the chemotherapeutic formulation.
25 . A method of relieving side effects of a chemotherapeutic compound in a mammal comprising co-administering a therapeutically effective amount of
i) an herbal preparation consisting essentially of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora ; and
ii) a chemotherapeutic formulation comprising a chemotherapeutic compound.
26 . The method of claim 25 , wherein the herbal preparation is administered via oral route, and the chemotherapeutic formulation is administered via oral or parenteral route.
27 . The method of claim 26 , wherein the herbal preparation is administered via oral route, and the chemotherapeutic formulation is administered via intravenous route.
28 . The method of claim 25 , wherein the herbal preparation consists of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora , and one or more pharmaceutically acceptable carriers.
29 . The method of claim 25 , wherein the herbal preparation is administered before the administration of the chemotherapeutic formulation.
30 . The method of claim 25 , wherein the herbal preparation is administered after the administration of the chemotherapeutic formulation.
31 . The method of claim 25 , wherein the herbal preparation is administered concurrently with the administration of the chemotherapeutic formulation.
32 . A method of enhancing anticancer activity of a chemotherapeutic compound in a mammal comprising administering a therapeutically effective amount of
i) an herbal preparation consisting essentially of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora ; and
ii) a chemotherapeutic formulation comprising a chemotherapeutic compound.
33 . The method of claim 32 , wherein the herbal preparation is administered via oral route, and the chemotherapeutic formulation is administered via oral or parenteral route.
34 . The method of claim 33 , wherein the herbal preparation is administered via oral route, and the chemotherapeutic formulation is administered via intravenous route.
35 . The method of claim 32 , wherein the herbal preparation consists of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora , and one or more pharmaceutically acceptable carriers.
36 . The method of claim 32 , wherein the herbal preparation is administered before the administration of the chemotherapeutic formulation.
37 . The method of claim 32 , wherein the herbal preparation is administered after the administration of the chemotherapeutic formulation.
38 . The method of claim 32 , wherein the herbal preparation is administered concurrently with the administration of the chemotherapeutic formulation.
39 . A method of treating cancer in a mammal comprising separately administering a therapeutically effective amount of
i) an herbal preparation consisting essentially of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora ; and
ii) a chemotherapeutic formulation comprising a chemotherapeutic compound.
40 . A method of relieving side effects of a chemotherapeutic compound in a mammal comprising separately administering a therapeutically effective amount of
i) an herbal preparation consisting essentially of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora ; and
ii) a chemotherapeutic formulation comprising a chemotherapeutic compound.
41 . A method of enhancing anticancer activity of a chemotherapeutic compound in a mammal comprising separately administering a therapeutically effective amount of
i) an herbal preparation consisting essentially of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora ; and
ii) a chemotherapeutic formulation comprising a chemotherapeutic compound.