IP Library Granted Patent US 10,799,232
Granted Patent B2
US 10,799,232 · App. 13/650,507 · Granted Oct 13, 2020

Method of endoscopic suturing

Inventors: J. Landon Gilkey (Austin, TX); Brett E. Naglreiter (Hollywood, FL); Peter K. Kratsch (Leander, TX); Donald K. Jones (Dripping Springs, TX); Vladimir Mitelberg (Austin, TX)
Assignee: Apollo Endosurgery US, Inc.
A61B17/0469A61B1/018A61B17/0487A61B17/068A61B17/0625A61B17/06123A61B17/00234A61B2017/00296A61B2017/00349A61B2017/0417A61B2017/0464A61B2017/0496A61B2017/0608A61B2017/06047A61B2017/0649A61B2017/2912
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Quick Facts
Patent No.
US 10,799,232
App. No.
13/650,507
Granted
Oct 13, 2020
Kind
B2
Abstract

An endoscopic suturing system and method are disclosed as are devices for use with the system and method such as a suture dispenser, a cinch device, and a tissue grasper. In one embodiment the suturing system includes a cap assembly arranged at the distal end portion of an endoscope or guide member, with the cap assembly including a rotatable needle holder. The needle holder is actuated through a transmission element extending outside the endoscope or guide member. A needle capture device may be inserted through a channel of the endoscope or guide member in order to capture a needle held in the needle holder when the needle holder is rotated so that the needle punctures tissue.

Claims (87)

1. A method of suturing tissue of a mammal using an endoscopic suturing system, comprising the follow steps:

(a) inserting an endoscope into a body with a suturing device coupled to the endoscope, the endoscope having an instrument channel extending therethrough;

(b) opening a needle arm of the suturing device having a removable needle removably coupled to the needle arm;

(c) drawing tissue at a desired suture site between the needle and a distal end of the endoscope;

(d) closing the needle arm of the suturing device such that the needle axially aligns with the instrument channel of the endoscope;

(e) piercing the tissue with the needle;

(f) recovering the needle within the distal end of the endoscope by using a needle capture device extended through the instrument channel of the endoscope;

(g) opening the needle arm to disengage the needle arm relative to the needle;

(h) closing the needle arm; and

(i) removing the suturing device from the body.

2. A method according to claim 1 , further comprising:

after step (b) and before step (c), engaging a tissue adjacent a desired suture site using a tissue grasper; and

after step (g) and before step (h), releasing the tissue from the tissue grasper.

3. A method according to claim 1 , further comprising:

(j) after step (h) and before step (i), inserting the needle into the needle arm endoscopically using the needle capture device; and

repeating steps (b) through (h) and (j) as needed.

4. A method according to claim 1 , wherein:

the needle arm is rigid.

5. A method according to claim 1 , wherein:

the needle arm is rigid,

the instrument channel opens at a distal end face of the endoscope, and

the needle arm extends through a predefined plane intersecting the distal end face of the endoscope.

6. A method of suturing tissue of a mammal using an endoscopic suturing system, comprising the follow steps:

(a) inserting a guide tube into a body;

(b) inserting a suturing device coupled to an endoscope into the guide tube and inserting the suturing device into the body;

(c) opening a needle holding arm of the suturing device having a removable needle clip;

(d) engaging a tissue adjacent a desired suture site using a tissue grasper;

(e) pushing the needle clip against tissue at a desired suture site;

(f) closing the needle holding arm of the suturing device such that the needle clip pierces the tissue and the needle clip axially aligns with an instrument channel of the endoscope;

(g) grasping the needle clip using a needle capture device extended through the instrument channel of the endoscope;

(h) opening the needle holding arm to remove it from tissue;

(i) releasing the needle clip from the needle capture device;

(j) releasing the tissue from the tissue grasper;

(k) closing the needle holding arm; and

(l) removing the suturing device from the body.

7. A method according to claim 6 , wherein:

the tissue grasper includes a helical coil with a sharp distal tip that is rotated into the tissue to engage the tissue.

8. A method according to claim 7 , wherein:

the suturing device is removed from the body while the needle arm is closed.

9. A method according to claim 6 , wherein:

said engaging tissue includes rotating the tissue grasper relative to the tissue.

10. A method according to claim 6 , further comprising:

after opening the needle arm, releasing the tissue grasper from the tissue.

11. A method according to claim 10 , wherein:

said releasing includes rotating the tissue grasper relative to the tissue.

12. A method according to claim 6 , wherein:

the needle holding arm is rigid.

13. A method of suturing tissue of a mammal using an endoscopic suturing system, comprising the follow steps:

(a) inserting an endoscope into a body with a suturing device coupled to the endoscope, the endoscope having an instrument channel;

(b) rotating open a rigid needle arm of the suturing device having a removable needle with a length of suture fixed thereto;

(c) engaging a tissue adjacent a desired suture site using a tissue grasper;

(d) drawing the engaged tissue into the path of the needle;

(e) rotating the rigid needle arm of the suturing device to cause the needle to pierce the tissue;

(f) engaging the needle with a needle capture device passed through the endoscope;

(g) recovering the needle with the needle capture device within the instrument channel;

(h) rotating open the rigid needle arm;

(i) closing the rigid needle arm; and

(j) removing the suturing device from the body.

14. A method according to claim 13 , wherein:

the tissue grasper includes a helical coil with a sharp distal tip that is rotated into the tissue to engage the tissue.

15. A method according to claim 13 , wherein:

said engaging tissue includes rotating the tissue grasper relative to the tissue.

16. A method according to claim 13 , further comprising:

after opening the needle arm, releasing the tissue grasper from the tissue.

17. A method according to claim 16 , wherein:

said releasing includes rotating the tissue grasper relative to the tissue.

18. A method according to claim 13 , wherein:

the suturing device is removed from the body while the needle arm is closed in a closed position.

19. A method according to claim 13 , wherein:

the instrument channel opens at a distal end face of the endoscope, and

the needle arm rotates in a path extending through a predefined plane intersecting the instrument channel.

20. A method of suturing tissue of a mammal using an endoscopic suturing system, comprising the following steps:

(a) inserting an endoscope into a body with a suturing device coupled at a distal end of the endoscope, the endoscope having an instrument channel that opens at a distal end face of the endoscope, the suturing device having a rigid needle arm and a needle removably coupled thereto, the needle arm rotatable through a predefined plane intersecting the instrument channel of the endoscope;

(b) rotating the needle arm of the suturing device into an open position to define a space between the needle and distal end of the endoscope;

(c) positioning tissue within the space between the needle in the open position and the distal end of the endoscope;

(d) rotating the needle arm into a closed position and toward the distal end of the endoscope in order to pierce the tissue with the needle;

(e) positioning the needle in alignment with the instrument channel of the endoscope;

(f) mechanically engaging the needle with an instrument extending through the instrument channel of the endoscope; and

(g) opening the needle arm to disengage the needle arm relative to the needle.

21. A method according to claim 20 , wherein:

a length of suture is fixed to the needle and extends through an instrument channel of the endoscope.

22. A method according to claim 20 , wherein:

the needle is recovered within the distal end of the endoscope using an instrument that is longitudinally displaceable within and removable from the endoscope.

23. A method according to claim 20 , further comprising:

after step (g), removing the disengaged needle arm from tissue.

24. A method according to claim 20 , further comprising:

after step (g), rotating the needle arm into a closed position, and removing the suturing device from the body with the needle arm in the closed position.

Assignments (14)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 27, 2023
From: APOLLO ENDOSURGERY US, INC.
To: APOLLO ENDOSURGERY, INC.
Reel/Frame 066128/0655 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 27, 2023
From: APOLLO ENDOSURGERY, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 066128/0812 →
TERMINATION AND RELEASE OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Apr 5, 2023
From: APOLLO ENDOSURGERY, INC.; APOLLO ENDOSURGERY US, INC.; APOLLO ENDOSURGERY INTERNATIONAL, LLC; LPATH THERAPEUTICS, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 063264/0046 →
RELEASE OF SECURITY INTEREST Recorded Dec 30, 2021
From: SLR INVESTMENT CORP. (F/K/A SOLAR CAPITAL LTD.)
To: APOLLO ENDOSURGERY US, INC.; APOLLO ENDOSURGERY INTERNATIONAL, LLC; APOLLO ENDOSURGERY, INC.; LPATH THERAPEUTICS INC.
Reel/Frame 058599/0297 →
SECURITY INTEREST Recorded Dec 23, 2021
From: APOLLO ENDOSURGERY, INC.; APOLLO ENDOSURGERY US, INC. (F/K/A LPATH, INC.)
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 058980/0199 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Apr 15, 2019
From: APOLLO ENDOSURGERY US, INC.
To: SOLAR CAPITAL LTD., AS COLLATERAL AGENT
Reel/Frame 048885/0687 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Mar 18, 2019
From: ATHYRIUM OPPORTUNITIES II ACQUISITION LP, AS ADMINISTRATIVE AGENT
To: APOLLO ENDOSURGERY US, INC. (F/K/A APOLLO ENDOSURGERY, INC.)
Reel/Frame 048622/0343 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Mar 18, 2019
From: ATHYRIUM OPPORTUNITIES II ACQUISITION LP, AS ADMINISTRATIVE AGENT
To: APOLLO ENDOSURGERY US, INC. (F/K/A APOLLO ENDOSURGERY, INC.)
Reel/Frame 048622/0328 →
CHANGE OF NAME Recorded Mar 27, 2017
From: APOLLO ENDOSURGERY, INC.
To: APOLLO ENDOSURGERY US, INC.
Reel/Frame 042106/0912 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Dec 30, 2016
From: APOLLO ENDOSURGERY US, INC.
To: ATHYRIUM OPPORTUNITIES II ACQUISITION LP, AS ADMINISTRATIVE AGENT
Reel/Frame 041224/0821 →
TERMINATION OF PATENT SECURITY INTEREST (RECORDED ON 12/3/13 AT REEL/FRAME 031756/0729 AND ON 1/2/14 AT REEL/FRAME 031910/0460) Recorded Mar 2, 2015
From: OXFORD FINANCE LLC, AS AGENT
To: APOLLO ENDOSURGERY, INC.
Reel/Frame 035120/0740 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Mar 2, 2015
From: APOLLO ENDOSURGERY, INC.
To: ATHYRIUM OPPORTUNITIES II ACQUISITION LP, AS ADMINISTRATIVE AGENT
Reel/Frame 035120/0843 →
SECURITY AGREEMENT Recorded Dec 3, 2013
From: APOLLO ENDOSURGERY, INC.
To: OXFORD FINANCE LLC, AS AGENT
Reel/Frame 031756/0729 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 16, 2012
From: GILKEY, J. LANDON; NAGLREITER, BRETT E.; KRATSCH, PETER K.; JONES, DONALD K.; MITELBERG, VLADIMIR
To: APOLLO ENDOSURGERY, INC.
Reel/Frame 029136/0789 →