IP Library Granted Patent US 9,205,098
Granted Patent B2
US 9,205,098 · App. 13/658,741 · Granted Dec 8, 2015

Anti-cancer therapies

Inventor: George Tidmarsh (Portola Valley, CA)
Assignee: Threshold Pharmaceuticals
A61K31/70A61K31/7028A61K31/7068
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Quick Facts
Patent No.
US 9,205,098
App. No.
13/658,741
Granted
Dec 8, 2015
Kind
B2
Abstract

Methods for the treatment of cancer are described. In particular, methods for treatment of cancer comprising administration of glufosfamide alone or in combination with another anticancer agent are disclosed.

Claims (8)

1. A pharmaceutical combination comprising:

a) an effective dose of glufosfamide, formulated for infusion; and

b) an effective dose of gemcitabine, formulated for infusion.

2. The pharmaceutical combination of claim 1 , packaged together.

3. The pharmaceutical combination of claim 2 , wherein the packaged pharmaceutical combination includes instructions for use of the combination in treating pancreatic cancer.

4. The pharmaceutical combination of claim 1 , wherein the effective dose of the glufosfamide is about 1.5 to about 6.0 g/m.

5. The pharmaceutical combination of claim 1 , wherein the effective dose of the gemcitabine is about 1.0 to 2.2 g/M.

6. The pharmaceutical combination of claim 4 , wherein the effective dose of the Gemcitabine is about 1.0 to 2.2 g/m.

Assignments (2)
SECURITY INTEREST Recorded Jun 16, 2023
From: MOLECULAR TEMPLATES, INC.
To: ANKURA TRUST COMPANY, LLC, AS COLLATERAL TRUSTEE
Reel/Frame 063979/0709 →
CHANGE OF NAME Recorded May 7, 2020
From: THRESHOLD PHARMACEUTICALS, INC.
To: MOLECULAR TEMPLATES, INC.
Reel/Frame 052607/0818 →
Continuity (3)
Continuation 10588409
Provisional Application 60542494 · Feb 6, 2004
Related Publication 20130045944A1 · Feb 21, 2013