IP Library Granted Patent US 9,296,684
Granted Patent B2
US 9,296,684 · App. 13/670,277 · Granted Mar 29, 2016

Allyl 2-cyanoacrylate prepolymer, preparation method thereof, and bioadhesive composition comprising the prepolymer

Inventors: Hun Kuk Park (Seoul, KR); Jin Ik Lim (Seoul, KR); Ji Hye Kim (Seoul, KR)
Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
C07C255/23
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Quick Facts
Patent No.
US 9,296,684
App. No.
13/670,277
Granted
Mar 29, 2016
Kind
B2
Abstract

An allyl 2-cyanoacrylate prepolymer, a preparation method thereof, and a bioadhesive composition including the prepolymer thus produced are provided, and more particularly, an allyl 2-cyanoacrylate prepolymer having a structure, in which at least one double bond in a molecule remains at an adjacent site to a cyano group prepared by causing a prepolymerization in a double bond moiety of an allyl group by pre-polymerizing through heating 2-cyanoacrylate having at least two double bonds in a molecule such as allyl 2-cyanoacrylate, a method for preparing the same, and a bioadhesive composition including the prepolymer thus produced are provided.

Claims (15)

1. A compound represented by the following Chemical Formula 1:

wherein,

n represents an integer between 2 to 1000; and

m represents an integer between 1 to 20.

2. The compound according to claim 1 , wherein the n represents an integer between 10 to 100.

3. The compound according to claim 1 , wherein the m represents an integer between 1 to 5.

4. The compound according to claim 1 , wherein a viscosity of the compound represented by the Chemical Formula 1 is 80 mPa·s to 400 mPa·s.

5. A bioadhesive composition comprising the compound according to any one of claims 1 to 3 and 4 .

6. A method for preparing a compound represented by the following Chemical Formula 1, the method comprising:

preparing the compound represented by the following Chemical Formula 1 by pre-polymerizing through heating a compound represented by the following Chemical Formula 2 in a vacuum state:

wherein,

n represents an integer between 2 to 1000; and

m represents an integer between 1 to 20.

7. The method according to claim 6 , wherein the heating is performed at 50° C. to 200° C.

8. The method according to claim 6 , wherein the heating is performed for 3 seconds to 2 hours.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 5, 2021
From: AZOTHBIO INC.
To: THERAMX INC.
Reel/Frame 056150/0426 →
CHANGE OF NAME Recorded Nov 24, 2020
From: MEDICOGEM, INC.
To: AZOTHBIO INC.
Reel/Frame 054514/0833 →
CHANGE OF NAME Recorded Nov 24, 2020
From: AZOTHBIO INC.
To: AZOTHBIO INC.
Reel/Frame 054514/0847 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2016
From: SAINT KHAL CO., LTD.
To: MEDICOGEM, INC.
Reel/Frame 039781/0098 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 3, 2016
From: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
To: SAINT KHAL CO., LTD.
Reel/Frame 039068/0543 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 6, 2013
From: PARK, HUN KUK; LIM, JIN IK; KIM, JI HYE
To: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
Reel/Frame 029765/0528 →
Priority Claims (1)
KR 10-2011-0115354 · Nov 7, 2011 · national
Continuity (1)
Related Publication 20130116465A1 · May 9, 2013