IP Library Granted Patent US 8,469,951
Granted Patent B2
US 8,469,951 · App. 13/677,633 · Granted Jun 25, 2013

Applicator and tissue interface module for dermatological device

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Quick Facts
Patent No.
US 8,469,951
App. No.
13/677,633
Granted
Jun 25, 2013
Kind
B2
Abstract

An tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Claims (25)

1. A tissue interface module for use with an applicator in a microwave-based tissue modification system, the tissue interface module comprising

an applicator chamber on a proximal side of the tissue interface module, the applicator chamber comprising:

an opening adapted to receive the applicator;

an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator;

a sealing member positioned at a proximal side of the applicator chamber;

a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator;

a tissue acquisition chamber on a distal side of the tissue interface module, the tissue acquisition chamber comprising a tissue acquisition opening on a distal side of the tissue interface module;

a flexible bio-barrier positioned between, and in fluid communication with, the applicator chamber and the tissue acquisition chamber, the flexible bio-barrier being substantially impermeable to air or fluids;

an airflow pathway within the tissue interface module, the airflow pathway connecting the applicator chamber and the tissue acquisition chamber;

a filter disposed in the airflow pathway connecting the applicator chamber and the tissue acquisition chamber, the filter being permeable to air and substantially impermeable to fluids.

2. The tissue interface module of claim 1 further comprising a variable flow restrictor between, and in communication with, the tissue acquisition chamber and the filter.

3. The tissue interface module of claim 2 wherein the variable flow restrictor is positioned in the airflow pathway.

4. The tissue interface module of claim 3 wherein the variable flow restrictor comprises a flexible element adapted to expand a flow opening in the airflow pathway in response to a pressure difference between the tissue acquisition chamber and the filter.

5. The tissue interface module of claim 1 wherein the sealing member forms at least a portion of the vacuum interface and is adapted to provide a substantially air tight seal against a sealing surface on the applicator when the tissue interface module is attached to the applicator with the attachment mechanism.

6. The tissue interface module of claim 1 wherein the attachment mechanism comprises

at least one attachment plate positioned in the applicator chamber, the attachment plate adapted to magnetically attach to elements of a magnetic circuit positioned on a distal end of the applicator.

7. The tissue interface module of claim 6 wherein the attachment plate comprises a magnetic element adapted to form a magnetic circuit with magnetic elements in the applicator.

8. The tissue interface module of claim 7 wherein the attachment plate comprises a ferromagnetic plate.

9. The tissue interface module of claim 6 further comprising a tissue interface module engagement surface adapted to engage with a corresponding applicator engagement surface on the applicator, the tissue interface module engagement surface being disposed at an angle of approximately 22.5 degrees with respect to the flexible bio-barrier.

10. The tissue interface module of claim 9 wherein the attachment plate comprises a ferromagnetic plate and the tissue interface module engagement surface comprises a surface of the ferromagnetic plate.

11. The tissue interface module of claim 6 further comprising a tissue interface module engagement surface adapted to engage with a corresponding applicator engagement surface on the applicator, the tissue interface module engagement surface being disposed at an angle of approximately 17.5 degrees to 27.5 degrees with respect to the flexible bio-barrier.

12. The tissue interface module of claim 1 further comprising a second filter disposed between, and communicating with, the applicator chamber and the tissue acquisition chamber, the second filter being permeable to air and substantially impermeable to fluids.

13. The tissue interface module of claim 12 wherein the filter and the second filter are positioned on opposing sides of the flexible bio-barrier.

14. The tissue interface module of claim 13 wherein the functional surface area of the bio-barrier is approximately the same as the functional surface area of the filter and the second filter combined.

15. The tissue interface module of claim 1 wherein the flexible bio-barrier is substantially transparent to microwave energy.

Assignments (17)
SECURITY INTEREST Recorded Oct 1, 2024
From: MIRADRY, INC.
To: WESTERN ALLIANCE BANK
Reel/Frame 068752/0533 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FUNDING IV TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0486 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FINANCIAL TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0573 →
RELEASE OF SECURITY INTEREST (TERM) Recorded Jun 22, 2021
From: MIDCAP FINANCIAL TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0044 →
RELEASE OF SECURITY INTEREST (REVOLVING) Recorded Jun 22, 2021
From: MIDCAP FUNDING IV TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0001 →
SECURITY INTEREST SUPPLEMENT (REVOLVING) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FUNDING IV TRUST, AS AGENT
Reel/Frame 055379/0016 →
REAFFIRMATION AGREEMENT AND AMENDMENT TO SECURITY AGREEMENT (TERM) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 055436/0001 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049649/0450 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049650/0001 →
SECURITY INTEREST Recorded Mar 13, 2019
From: MIDCAP FUNDING X TRUST (AS SUCCESSOR TO MIDCAP FINANCIAL TRUST)
To: MIDCAP FUNDING IV TRUST, SUCCESSOR AGENT
Reel/Frame 048588/0123 →
CHANGE OF NAME Recorded May 3, 2018
From: MIRAMAR TECHNOLOGIES, INC.
To: MIRADRY, INC.
Reel/Frame 045707/0330 →
CHANGE OF NAME Recorded May 3, 2018
From: MIRAMAR LABS, INC.
To: MIRAMAR TECHNOLOGIES, INC.
Reel/Frame 045706/0690 →
RELEASE OF SECURITY INTEREST Recorded Aug 18, 2017
From: OXFORD FINANCE LLC
To: MIRAMAR TECHNOLOGIES, INC. F/K/A MIRAMAR LABS, INC.
Reel/Frame 043331/0505 →
SECURITY INTEREST Recorded Jul 28, 2017
From: SIENTRA, INC.; MIRAMAR LABS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 043361/0130 →
SECURITY INTEREST Recorded Jul 28, 2017
From: SIENTRA, INC.; MIRAMAR LABS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 043362/0811 →
SECURITY INTEREST Recorded Mar 8, 2017
From: MIRAMAR TECHNOLOGIES, INC.
To: OXFORD FINANCE LLC
Reel/Frame 041510/0935 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 8, 2013
From: BEN-HAIM, YOAV; BENTLEY, PETER J.; CHUN, DONG HOON; FRANCIS, DANIEL; JOHNSON, JESSI E.; SHAN, KEVIN; SU, TED; KIM, STEVEN
To: MIRAMAR LABS, INC.
Reel/Frame 030378/0010 →