Hemostatic sponge
View Patent ↗A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.
1. A hemostatic sponge comprising:
a substrate comprising a sponge matrix;
a kaolin material applied to the substrate; and
a glycerol binder configured to retain the kaolin material to the sponge matrix;
wherein the hemostatic sponge is subjected to a drying process after the kaolin material is applied to the sponge matrix; and
wherein the sponge is configured such that when treating a bleeding wound, application of the sponge is capable of causing blood to be absorbed into the sponge matrix of the substrate and causing at least a portion of the kaolin material to come into contact with blood to assist in accelerating clotting.
2. The hemostatic sponge of claim 1 , further comprising a pharmaceutically-active composition selected from the group consisting of antibiotics, antifungal agents, antimicrobial agents, anti-inflammatory agents, analgesics, antihistamines, compounds containing silver or copper ions, and combinations of the foregoing compositions.
3. The hemostatic sponge of claim 1 , wherein the substrate is fabricated from a material selected from the group consisting of cotton, silk, wool, plastic, cellulose, rayon, polyester, and combinations of the foregoing.
4. The hemostatic sponge of claim 1 , wherein the substrate is flexible to allow the substrate to form to a shape of the bleeding wound and to retain a shape of the bleeding wound.
5. The hemostatic sponge of claim 1 , further comprising a release agent disposed on a surface of the hemostatic sponge.
6. The hemostatic sponge of claim 5 , wherein the release agent is selected from the group consisting of polyvinyl alcohol, glycerol, silicone, carboxymethyl cellulose, and gelatinized starch.
7. The hemostatic sponge of claim 1 , wherein the kaolin material comprises particles having diameters of less than about 0.2 mm.
8. The hemostatic sponge of claim 1 , wherein the glycerol binder is applied to the substrate by a spraying process.
9. The hemostatic sponge of claim 1 , wherein the glycerol binder and the kaolin material are applied to the substrate by a spraying process.
10. The hemostatic sponge of claim 1 , wherein the glycerol binder is applied to the substrate by immersing the substrate in a liquid comprising the glycerol binder.
11. The hemostatic sponge of claim 1 , wherein the glycerol binder and the kaolin material are applied to the substrate by immersing the substrate in a liquid comprising the glycerol binder and the kaolin material.
12. A hemostatic sponge comprising:
a sponge matrix;
a clay material applied to the sponge matrix; and
a calcium alginate binder to bind the clay material to the sponge matrix; and
the sponge is configured such that when treating bleeding, application of the sponge is capable of causing at least a portion of the clay material to come into contact with blood from a bleeding wound to assist in accelerating clotting.
13. The hemostatic sponge of claim 12 , wherein the clay material is selected from the group consisting of attapulgite, bentonite, kaolin, kaolinite, and combinations of the foregoing materials.
14. The hemostatic sponge of claim 12 , further comprising a pharmaceutically-active composition selected from the group consisting of antibiotics, antifungal agents, antimicrobial agents, anti-inflammatory agents, analgesics, antihistamines, compounds containing silver or copper ions, and combinations of the foregoing compositions.
15. The hemostatic sponge of claim 12 , wherein the sponge matrix is fabricated from a material selected from the group consisting of cotton, silk, wool, plastic, cellulose, rayon, polyester, and combinations of the foregoing.
16. The hemostatic sponge of claim 12 , wherein the sponge matrix is flexible to allow the sponge matrix to form to a shape of the bleeding wound and to retain the shape of the bleeding wound.
17. The hemostatic sponge of claim 12 , further comprising a release agent disposed on the hemostatic sponge.
18. The hemostatic sponge of claim 17 , wherein the release agent is selected from the group consisting of polyvinyl alcohol, glycerol, silicone, carboxymethyl cellulose, and gelatinized starch.
19. The hemostatic sponge of claim 12 , wherein the clay material comprises kaolin particles having diameters of less than about 0.2 mm.
20. The hemostatic sponge of claim 19 , wherein the sponge matrix is flexible to allow the substrate to form to and retain the shape of the bleeding wound.
21. A hemostatic device comprising:
a sponge material;
a hemostatic material comprising kaolin; and
a calcium alginate binder applied to the sponge material to bind the hemostatic material to the sponge material, wherein the calcium alginate binder and the hemostatic material are applied by spraying or immersion; and
wherein the device is configured such that when treating bleeding, application of the device is capable of causing blood to be absorbed within the device and of causing at least a portion of the hemostatic material to come into contact with blood to assist in accelerating clotting.