Aseptic coupling devices

1. An aseptic coupling device, comprising:

an inner member defining a fluid passage therethrough;

a seal member coupled to a front surface of the inner member, the seal member having a cross-sectional area including a first end portion, a middle portion, and a second end portion opposite the first end portion, the middle portion being thinner in radial dimension than the first and second end portions, the middle portion defining curved inner and outer bounds defined by arcs of two nonconcentric circles when the seal is in an uncompressed relaxed state, the relaxed state occurring when the aseptic coupling device is uncoupled from a mating aseptic coupling device,

wherein the center of the circle defining the curved outer bound is located outside the outer bound of the seal;

wherein a first radius of the arced outer bound differs from a second radius of the arced inner bound; and

a membrane coupled to the front surface of the inner member to cover the seal member.

2. The aseptic coupling device of claim 1 , further comprising a locking ring positioned to rotate about the inner member.

3. The aseptic coupling device of claim 2 , wherein the inner member is sized to be received in a member of another aseptic coupling device to form a pre-coupled state, wherein, when the membrane is removed, the seal member engages a second seal member of the other aseptic device, and wherein, upon turning of the locking ring, the seal member and the second seal member are compressed to form a coupled state in which a sterile flow path is created between the aseptic coupling device and another aseptic coupling device.

4. The aseptic coupling device of claim 1 , wherein the seal member is configured to be compressed against another seal member to form a coupled state in which a sterile flow path is created between the aseptic coupling device and another aseptic coupling device.

5. The aseptic coupling device of claim 1 , wherein the seal member is configured to be compressed against another seal member to form a coupled state in which a sterile flow path is created between the aseptic coupling device and another aseptic coupling device.

6. The aseptic coupling device of claim 1 , wherein the first radius of the arced outer bound is smaller than the second radius of the arced inner bound.

7. A method for forming a sterile connection, the method comprising:

forming a seal member, the seal member having a cross-sectional area including a first end portion, a middle portion, and a second end portion opposite the first end portion, the middle portion being thinner in radial dimension than the first and second end portions, the middle portion defining curved outer and inner bounds defined by arcs of two nonconcentric circles when the seal is in an uncompressed relaxed state, the relaxed state occurring when the aseptic coupling device is uncoupled from a mating aseptic coupling device,

wherein the center of the circle defining the curved outer bound is located outside the outer bound of the seal;

wherein a first radius of the arced outer is smaller than a second radius of the arced inner bound;

positioning the seal member in a first aseptic coupling device;

inserting the first aseptic coupling device into a second aseptic coupling device; and

removing a first membrane from the first aseptic coupling device and a second membrane from the second aseptic coupling device.

8. The method of claim 7 , further comprising configuring the seal member to be compressed against another seal member to form a coupled state in which a sterile flow path is created between the first aseptic coupling device and a second aseptic device.

9. The method of claim 7 , further comprising rotating a locking clip on the first aseptic coupling device to compress a first seal member of the first aseptic coupling device with a second seal member of the second aseptic coupling device to form a sterile fluid passageway.

10. A method for forming a sterile connection, the method comprising:

forming a seal member, the seal member having a cross-sectional area including a first end portion, a middle portion, and a second end portion opposite the first end portion, the middle portion being thinner in radial dimension than the first and second end portions, the middle portion defining curved outer and inner bounds defined by arcs of two nonconcentric circles when the seal is in an uncompressed relaxed state, the relaxed state occurring when the aseptic coupling device is uncoupled from a mating aseptic coupling device,

wherein the center of the circle defining the curved outer bound is located outside the outer bound of the seal;

wherein a first radius of the arced outer is smaller than a second radius of the arced inner bound;

positioning the seal member in a first aseptic coupling device;

forming a second seal member having an identical shape to that of the seal member; and

positioning the second seal member in a mating aseptic coupling device.