IP Library › Granted Patent US 8,957,052
Granted Patent B2
US 8,957,052 · App. 13/696,345 · Granted Feb 17, 2015

Methods and compositions for the treatment of fluid accumulation in and/or under the retina

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Quick Facts
Patent No.
US 8,957,052
App. No.
13/696,345
Granted
Feb 17, 2015
Kind
B2
Abstract

The present invention provides methods and compositions for the treatment of fluid accumulation in and/or under the retina.

Claims (4)

1. A method for treating a patient who has central serous chorioretinitis comprising administering to the patient a mineralocorticoid receptor (MR) antagonist or an inhibitor of mineralocorticoid receptor gene expression in an amount effective to treat fluid accumulation in and/or under the retina that is associated with central serous chorioretinitis.

2. The method according to claim 1 , wherein the mineralocorticoid receptor (MR) antagonist or the inhibitor of mineralocorticoid receptor gene expression is administered to the eye of the subject in need of treatment.

3. The method according to claim 1 , wherein the mineralocorticoid receptor (MR) antagonist is a spirolactone-type steroidal compound.

4. The method according to claim 3 , wherein the mineralocorticoid receptor (MR) antagonist is eplerenone.

Assignments (5)
CHANGE OF NAME Recorded May 12, 2022
From: UNIVERSITE DE PARIS
To: UNIVERSITÉ PARIS CITÉ
Reel/Frame 059988/0388 →
MERGER Recorded May 12, 2022
From: UNIVERSITE PARIS DESCARTES
To: UNIVERSITE DE PARIS
Reel/Frame 060044/0856 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE PREVIOUSLY RECORDED ON REEL 034660 FRAME 0790. ASSIGNOR(S) HEREBY CONFIRMS THE OWNERSHIP IS SHARED AMONGST THE 3 ASSIGNEES.. Recorded Mar 2, 2016
From: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
To: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE); UNIVERSITE PARIS DESCARTES; ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
Reel/Frame 037976/0401 →
JOINT OWNERSHIP ASSIGNMENT Recorded Dec 17, 2014
From: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
To: UNIVERSITE PARIS DESCARTES; ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
Reel/Frame 034660/0790 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 21, 2014
From: BEHAR-COHEN, FRANCINE; FARMAN, NICOLETTE; JAISSER, FREDERIC
To: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
Reel/Frame 033990/0011 →