PROCESSES FOR THE PRODUCTION OF HYDROGENATED PRODUCTS AND DERIVATIVES THEREOF

1 . A process for producing a hydrogenated product from a clarified DAA-containing fermentation broth or MAA-containing fermentation broth comprising:

(a) distilling the broth under super atmospheric pressure at a temperature of >100° C. to about 300° C. to form an overhead that comprises water and ammonia, and a liquid bottoms that comprises AA and at least about 20 wt % water;

(b) cooling and/or evaporating the bottoms to attain a temperature and composition sufficient to cause the bottoms to separate into a liquid portion and a solid portion that is substantially pure AA;

(c) separating the solid portion from the liquid portion;

(d) hydrogenating the solid portion, in the presence of at least one hydrogenation catalyst to produce the hydrogenated product comprising at least one of CLO or HDO; and

(e) recovering the hydrogenated product.

2 . A process for producing a hydrogenated product from a clarified DAA-containing fermentation broth or MAA-containing fermentation broth comprising:

(a) adding an ammonia separating solvent and/or a water azeotroping solvent to the broth;

(b) distilling the broth at a temperature and pressure sufficient to form an overhead that comprises water and ammonia, and a liquid bottoms that comprises AA and at least about 20 wt % water;

(c) cooling and/or evaporating the bottoms to attain a temperature and composition sufficient to cause the bottoms to separate into a liquid portion and a solid portion that is substantially pure AA;

(d) separating the solid portion from the liquid portion;

(e) hydrogenating the solid portion in the presence of at least one hydrogenation catalyst to produce the hydrogenated product comprising at least one of CLO or HDO; and

(f) recovering the hydrogenated product.

3 . The process of claim 1 , further comprising contacting the CUD with an ammonia source at elevated temperature and pressure to produce CL.

4 . The process of claim 3 , further comprising converting the CL to NYLON 6.

5 . The process of claim 1 , further comprising converting the CLO to poly-CLO.

6 . The process of claim 1 , further comprising:

contacting the CLO with hydrogen and at least one hydrogenation catalyst to produce a hydrogenated product comprising HDO; and

recovering the HDO.

7 . The process of claim 1 , wherein the fermentation broth is obtained by fermenting a carbon source in the presence of a microorganism selected from the group consisting of Candida tropicalis (Castellani) Berkhout, anamorph strain OH23 having ATCC accession number 24887; E. coli strain AB2834/pKD136/pKD8.243A/pKD8.292 having ATCC accession number 69875; E. coli cosmid clone 5B12 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO: 1. E. coli cosmid clone 5F5 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO: 1; E. coli cosmid clone 8F6 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO: 1; E. coli cosmid clone 14D7 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO: 1; and Verdezyne Yeast.

8 . The process of claim 2 , wherein distilling the broth is carried out in the presence of an ammonia separating solvent which is at least one selected from the group consisting of diglyme, triglyme, tetraglyme, sulfoxides, amides, sulfones, polyethyleneglycol (PEG), butoxytriglycol, N-methylpyrolidone (NMP), ethers, and methyl ethyl ketone (MEK) or in the presence of a water azeotroping solvent which is at least one selected from the group consisting of toluene, xylene, methylcyclohexane, methyl isobutyl ketone, hexane, cyclohexane and heptane.

9 . The process of claim 2 , further comprising contacting the CLO with an ammonia source at elevated temperature and pressure to produce CL.

10 . The process of claim 9 , further comprising converting the CL to NYLON 6.

11 . The process of claim 2 , further comprising converting the CLO to poly-CLO.

12 . The process of claim 2 , further comprising:

contacting the CLO with hydrogen and at least one hydrogenation catalyst to produce hydrogenated product comprising HDO; and

recovering the HDO.

13 . The process of claim 2 , wherein the fermentation broth is obtained by fermenting a carbon source in the presence of a microorganism selected from the group consisting of Candida tropicalis (Castellani) Berkhout, anamorph strain OH23 having ATCC accession number 24887; E. coli strain AB2834/pKD136/pKD8.243A/pKD8.292 having ATCC accession number 69875; E. coli cosmid clone 5B12 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO: 1, E. coli cosmid clone 5F5 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO 1; E. coli cosmid clone 8F6 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO: 1; E. coli cosmid clone 1407 comprising a vector expressing the cyclohexanone monoxygenase encoded by SEQ ID NO: 1; and Verdezyne Yeast.