IP Library Granted Patent US 8,768,472
Granted Patent B2
US 8,768,472 · App. 13/705,021 · Granted Jul 1, 2014

Multi-frequency neural treatments and associated systems and methods

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,768,472
App. No.
13/705,021
Granted
Jul 1, 2014
Kind
B2
Abstract

Multi-frequency neural treatments and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes at least reducing patient pain by applying a first electrical signal to a first target location of the patient's spinal cord region at a frequency in a first frequency range of up to about 1,500 Hz, and applying a second electrical signal to a second target location of the patient's spinal cord region at a frequency in a second frequency range of from about 2,500 Hz to about 100,000 Hz.

Claims (24)

1. A method for alleviating patient pain or discomfort, without relying on paresthesia or tingling to mask the patient's sensation of the pain, comprising:

implanting a percutaneous lead in the patient's epidural space, wherein the percutaneous lead includes at least one electrode, and wherein implanting the percutaneous lead includes positioning the at least one electrode proximate to a target location in the patient's spinal cord region and outside the sacral region;

implanting a signal generator in the patient;

electrically coupling the percutaneous lead to the signal generator; and

programming the signal generator to generate and deliver an electrical therapy signal to the spinal cord region, via the at least one electrode, wherein at least a portion of the electrical therapy signal is at a frequency in a frequency range of from about 2,500 Hz to about 100,000 Hz.

2. The method of claim 1

wherein the target location includes the patient's dorsal column.

3. The method of claim 1

wherein the at least one electrode is located toward a distal end of the percutaneous lead.

4. The method of claim 1 , wherein at least a portion of the electrical therapy signal is at a frequency in a frequency range of from about 2,500 Hz to about 20,000 Hz.

5. The method of claim 1 , wherein at least a portion of the electrical therapy signal is at a frequency in a frequency range of from about 3,000 Hz to about 10,000 Hz.

6. The method of claim 1 , further comprising:

applying a stimulation signal to the patient's spinal cord region, wherein the stimulation signal is at a frequency in a frequency range of from about 40 Hz to about 500 Hz.

7. The method of claim 1 , wherein the electrical therapy signal is applied continuously.

8. The method of claim 1 , wherein the electrical therapy signal is applied discontinuously so as to include periods when the electrical therapy signal is applied, and periods when the electrical therapy signal is terminated.

9. The method of claim 8 , wherein the periods when the electrical therapy signal is applied range from a few seconds to a few hours.

10. The method of claim 1 , wherein the electrical therapy signal is applied discontinuously so as to include periods when the electrical therapy signal is applied, and periods when the electrical therapy signal is terminated according to a duty cycle.

11. A method for alleviating patient pain or discomfort, without relying on paresthesia or tingling to mask the patient's sensation of the pain, comprising:

implanting a percutaneous lead in the patient's epidural space, wherein the percutaneous lead includes at least one electrode, and wherein implanting the percutaneous lead includes positioning the at least one electrode proximate to a target location in the patient's spinal cord region and outside the scaral region;

implanting a signal generator in the patient;

electrically coupling the percutaneous lead to the signal generator; and

programming the signal generator to generate and deliver an electrical therapy signal to the spinal cord region, via the at least one electrode, wherein at least a portion of the electrical therapy signal is at a frequency in a frequency range of from about 2,500 Hz to about 100,000 Hz and a current amplitude between about 2 mA and about 20 mA.

12. The method of claim 11 , further comprising:

programming the signal generator to generate and deliver the electrical therapy signal at a duty cycle of less than 50%.

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Apr 4, 2025
From: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
To: NEVRO CORP.
Reel/Frame 070743/0001 →
PATENT SECURITY AGREEMENT Recorded Dec 1, 2023
From: NEVRO CORP.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 065744/0302 →
CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY NAME PREVIOUSLY RECORDED ON REEL 030882 FRAME 0424. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jul 1, 2019
From: FANG, ZI-PING; CAPARSO, ANTHONY V.; ERICKSON, BRIAN J.; ALATARIS, KONSTANTINOS; WALKER, ANDRE B.
To: NEVRO CORP.
Reel/Frame 049645/0410 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNMENT PREVIOUSLY RECORDED AT REEL: 030882 FRAME: 0424. ASSIGNOR(S) HEREBY CONFIRMS THE CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY DATA NAME.. Recorded Dec 18, 2017
From: FANG, ZI-PING; CAPARSO, ANTHONY V.; ERICKSON, BRIAN J.; ALATARIS, KONSTANTINOS; WALKER, ANDRE B.
To: NEVRO CORP.
Reel/Frame 044904/0963 →
RELEASE OF SECURITY INTEREST Recorded Jun 27, 2016
From: CRG SERVICING LLC
To: NEVRO CORP.
Reel/Frame 039168/0890 →
ASSIGNMENT AGREEMENT (REAFFIRMATION) Recorded Jun 13, 2016
From: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: CRG SERVICING LLC,
Reel/Frame 038984/0865 →
SECURITY INTEREST Recorded Dec 12, 2014
From: NEVRO CORP.
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 034619/0546 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2013
From: FANG, ZI-PING; CAPARSO, ANTHONY V.; ERICKSON, BRIAN J.; ALATARIS, KONSTANTINOS; WALKER, ANDRE B.
To: NEVRO CORPORATION
Reel/Frame 030882/0424 →