IP Library Granted Patent US 8,459,470
Granted Patent B2
US 8,459,470 · App. 13/708,653 · Granted Jun 11, 2013

Functionalized nonwoven article

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Quick Facts
Patent No.
US 8,459,470
App. No.
13/708,653
Granted
Jun 11, 2013
Kind
B2
Abstract

A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.

Claims (22)

1. A filter device comprising:

a fluid inlet;

a fluid outlet;

a filter media fluidly connecting the fluid inlet and the fluid outlet; and

wherein the filter media comprises

a nonwoven substrate having average fiber diameter of 1 to 6 micrometers, and a void volume of 50 to 95%, a tensile strength of at least 4.0 Newtons prior to grafting and a polymer grafted to the surface of the nonwoven substrate; and

wherein the grafted polymer comprises polymerized monomer units of:

a) 80 to 98 wt. % of grafting aminoalkyl (meth)acryloyl monomers,

b) 2 to 20 wt. % of grafting poly(alkylene oxide) monomers;

c) 0 to 10 wt. % of second hydrophilic monomers; and

wherein the filter device further comprises

a separator element;

an edge seal; and

wherein the separator element comprises

a central core in fluid communication with the fluid inlet;

a first side; and

a second side; and

wherein the filter media further comprises

a first media disk positioned on the first side of the separator element and having an outer circumferential edge and an inner circumferential edge; and

a second media disk positioned on the second side of the separator element and having an outer circumferential edge and an inner circumferential edge; and

wherein the outer circumferential edges of the first and second media disks are connected by the edge seal and the inner circumferential edges of the first and second media disks are connected to the central core.

2. The filter device of claim 1 wherein the first and second media disks further comprise a microporous membrane layer positioned downstream of the grafted nonwoven substrate.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2024
From: 3M INNOVATIVE PROPERTIES COMPANY
To: SOLVENTUM INTELLECTUAL PROPERTIES COMPANY
Reel/Frame 066430/0287 →