Phytonutrient compositions and methods to protect against radical mediated cellular and DNA damage

1. A method for reducing or treating genetic damage induced by environmental agents in a mammal, wherein said method comprises administering a composition in a dosage form suitable for oral administration, said composition comprising a phytonutrient blend consisting essentially of:

(a) Acacia nilotica extract;

(b) artichoke extract;

(c) blueberry extract;

(d) catechins;

(e) chlorogenic acid;

(f) cinnamon;

(g) ellagic acid;

(h) grape seed extract;

(i) hesperidin;

(j) Momordica extract;

(k) prune extract;

(l) rosemary extract; and

(m) watercress extract;

wherein in the phytonutrient blend: the Acacia nilotica extract (a) is present in an amount of from about 0.5 mg to 10 mg; the artichoke extract (b) is present in an amount of from about 0.5 mg to 10 mg; the blueberry extract (c) is present in an amount of from about 1 mg to 25 mg; the catechins (d) is present in an amount of from about 2.5 mg to 25 mg; the chlorogenic acid (e) is present in an amount of from about 25 mg to 75 mg; the cinnamon (f) is present in an amount of from about 0.5 mg to 10 mg; the ellagic acid (g) is present in an amount of from about 10 mg to 100 mg; the grape seed extract (h) is present in an amount of from about 2.5 mg to 50 mg; the hesperidin (i) is present in an amount of from about 15 mg to 120 mg; the Momordica extract (j) is present in an amount of from about 0.5 mg to 10 mg; the prune extract (k) is present in an amount of from about 0.5 mg to 10 mg; the rosemary extract (l) is present in an amount of from about 0.5 mg to 10 mg; and the watercress extract (m) is present in an amount of from about 0.5 mg to 10 mg.

2. The method of claim 1 , wherein the step of administering is defined as orally administering.

3. The method of claim 2 , wherein the dosage form of the composition is selected from the group consisting of capsules, caplets, gelcaps, cachets, pills, and tablets.

4. The method of claim 3 , wherein the dosage form is a tablet.

5. The method of claim 4 , wherein the tablet is coated, and optionally scored.

6. The method of claim 2 , wherein the dosage form of the composition is selected from the group consisting of solutions, suspensions, and emulsions.

7. The method of claim 2 , wherein the dosage form of the composition is selected from the group consisting of elixirs, powders, lozenges, micronized particles, and osmotic delivery systems.

8. The method of claim 1 , wherein the Acacia nilotica extract (a) is derived from gum resin, bark powder, or heartwood powder.

9. The method of claim 1 , wherein the Acacia nilotica extract (a) is selected from acidic, alkaline, polar solvent, nonpolar solvent, or gastric fluid extracts.

10. The method of claim 1 , wherein the composition is administered as a capsule, a caplet, a gel cap, a cachet, a pill, a tablet, a solution, a suspension, an oil-in-water emulsion, or a water-in-oil emulsion.

11. The method of claim 1 , wherein the composition is administered prophylactically.

12. The method of claim 1 , wherein the composition is administered palliatively.

13. The method of claim 1 , wherein the mammal is a human.

14. The method of claim 1 , wherein the composition further comprises a pharmaceutically acceptable vehicle.

15. The method of claim 14 , wherein the pharmaceutically acceptable vehicle is selected from the group consisting of diluents and excipients.

16. The method of claim 1 , wherein the composition further comprises one or more accessory ingredients.

17. The method of claim 16 , wherein the accessory ingredient(s) is(are) selected from the group consisting of a binder, a lubricant, an inert diluent, a preservative, a surface active agent, and a dispersing agent.

18. The method of claim 1 , wherein the phytonutrient blend consists of components (a) to (m).