IP Library Granted Patent US 9,126,050
Granted Patent B2
US 9,126,050 · App. 13/736,096 · Granted Sep 8, 2015

Non-invasive vagus nerve stimulation devices and methods to treat or avert atrial fibrillation

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Quick Facts
Patent No.
US 9,126,050
App. No.
13/736,096
Granted
Sep 8, 2015
Kind
B2
Abstract

Energy is transmitted noninvasively to a patient using electrode-based stimulation devices or magnetic stimulation devices that are designed to non-invasively stimulate nerves selectively. The devices produce impulses that are used to treat atrial fibrillation, by stimulating a vagus nerve of a patient. The devices are also used to forecast the imminent onset of atrial fibrillation and then avert it by stimulating a vagus nerve.

Claims (9)

1. A method of treating atrial fibrillation in a patient, comprising:

positioning a device in contact with an outer skin surface of a neck of the patient;

generating an electric current within the device, wherein the electric current comprises bursts of pulses with each burst having a frequency of about 15 to about 50 Hz and each pulse having a pulse duration of about 50 to about 1000 microseconds; and

transmitting the electric current through an electrically conductive fluid within the device transcutaneously through the neck of the patient to a vagus nerve in the patient, wherein the electric current is sufficient to terminate an episode of atrial fibrillation.

2. The method of claim 1 wherein the generating step is carried out with a pulse generator coupled to one or more electrodes.

3. The method of claim 1 further comprising generating an electrical field at or near the device and shaping the electrical field such that the electrical field is sufficient to modulate the vagus nerve; and wherein the electric field is not sufficient to substantially modulate a nerve or muscle between the outer skin surface and the vagus nerve.

4. The method of claim 1 wherein the electric current is transmitted to the right vagus nerve of the patient.

5. The method of claim 1 wherein each burst of pulses contains from 2 to 20 pulses.

6. The method of claim 1 wherein the pulses are full sinusoidal waves.

Assignments (4)
SECURITY INTEREST Recorded Aug 12, 2025
From: ELECTROCORE, INC.
To: AVENUE VENTURE OPPORTUNITIES FUND II, L.P.
Reel/Frame 072452/0559 →
CHANGE OF NAME Recorded Feb 20, 2019
From: ELECTROCORE, LLC
To: ELECTROCORE, INC.
Reel/Frame 048389/0609 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 25, 2013
From: SIMON, BRUCE J.; ERRICO, JOSEPH P.; RAFFLE, JOHN T.
To: ELECTROCORE, LLC
Reel/Frame 031673/0571 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 18, 2013
From: SIMON, BRUCE J.; ERRICO, JOSEPH P.; RAFFLE, JOHN T.
To: ELECTROCORE LLC
Reel/Frame 030026/0042 →