Method and apparatus for loading a beneficial agent into an expandable medical device

1. A method for loading a beneficial agent into a medical device, the method comprising:

mounting the medical device over a mandrel, the medical device including a plurality of through-holes extending through a thickness of a wall of the medical device from a first side to a second side, the mandrel having an resilient outer jacket;

sealing one of the plurality of through-holes at the first side of the respective through-hole with the resilient outer jacket of the mandrel to substantially prevent a beneficial agent from leaking at an interface of the resilient outer jacket and the medical device to prevent the beneficial agent from passing to the first side of the respective through-hole;

at least partially filling the respective through-hole with the beneficial agent delivered from an automated micro-jetting dispenser;

substantially solidifying the beneficial agent; and

removing the resilient outer jacket of the mandrel from the respective through-hole.

2. The method of claim 1 , wherein the resilient outer jacket of the mandrel is formed of a rubber-like material.

3. The method of claim 2 , wherein the resilient outer jacket of the mandrel is formed of the rubber-like material, and the medical device is a stent.

4. The method of claim 1 , wherein the plurality of through-holes are formed by lasercutting.

5. The method of claim 1 , wherein the medical device is a metallic medical device.

6. The method of claim 1 , wherein the respective through-hole has an area of at least 5×10 −6 square inches.

7. The method of claim 1 , wherein the beneficial agent includes a drug and a polymer matrix.

8. The method of claim 1 , wherein the step of substantially solidifying includes drying the beneficial agent.

9. The method of claim 1 , wherein the micro jetting dispenser is a piezoelectric micro jetting dispenser.