IP Library Granted Patent US 8,913,716
Granted Patent B2
US 8,913,716 · App. 13/739,590 · Granted Dec 16, 2014

System and method of calculating dose uncertainty

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Quick Facts
Patent No.
US 8,913,716
App. No.
13/739,590
Granted
Dec 16, 2014
Kind
B2
Abstract

A dose calculation tool operable to generate a variance map that represents a dose uncertainty. The variance map illustrates on a point-by-point basis where high uncertainty in the dose may exist and where low uncertainty in the dose may exist. The dose uncertainty is a result of an error in one or more data parameters related to a delivery parameter or a computational parameter.

Claims (20)

1. A method of detecting a delivery error in a radiation delivery device, the method comprising using a computer to carry out the steps of:

generating a treatment plan for a patient, the treatment plan including an intended fluence;

delivering radiation to the patient according to the treatment plan;

acquiring output fluence information from the radiation delivery device after delivery of the treatment plan;

comparing the output fluence information and the intended fluence to determine a fluence variance; and

applying a dose calculation algorithm to the fluence variance to generate a dose variance map.

2. The method of claim 1 wherein the fluence variance is based on feedback from the radiation delivery device over the course of a plurality of treatments.

3. The method of claim 1 further comprising modifying the treatment plan based on the fluence variance.

4. The method of claim 1 further comprising generating a new treatment plan based on the fluence variance.

5. The method of claim 1 further comprising selecting a different radiation delivery device to deliver the treatment plan based on the fluence variance.

6. The method of claim 1 further comprising modifying the treatment plan based on anticipated changes to the radiation delivery device.

7. The method of claim 1 further comprising displaying the dose variance map.

8. The method of claim 1 wherein the dose variance map represents an uncertainty indication in the dose to be delivered to the patient, the uncertainty indication related to a data parameter of the radiation delivery device.

9. The method of claim 8 wherein the data parameter includes a combination of multiple single data parameters.

10. The method of claim 8 wherein the data parameter is fluence.

11. The method of claim 8 wherein the data parameter is linac output.

12. The method of claim 8 wherein the data parameter is leaf timing.

13. The method of claim 8 wherein the data parameter is jaw position.

14. The method of claim 8 wherein the data parameter is couch position.

15. The method of claim 8 wherein the data parameter is gantry position.

Assignments (12)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2025
From: ACCURAY INCORPORATED
To: ACCURAY LLC
Reel/Frame 072189/0891 →
RELEASE OF SECURITY INTEREST Recorded Jun 6, 2025
From: FIRST-CITIZENS BANK & TRUST COMPANY
To: ACCURAY INCORPORATED
Reel/Frame 071638/0034 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2023
From: TOMOTHERAPY INCORPORATED
To: ACCURAY INCORPORATED
Reel/Frame 064218/0337 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FINANCIAL TRUST
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0751 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING X TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0559 →
SECURITY INTEREST Recorded May 14, 2021
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: SILICON VALLEY BANK, AS ADMINISTRATIVE AND COLLATERAL AGENT
Reel/Frame 056247/0001 →
ASSIGNMENT OF SECURITY AGREEMENTS Recorded Mar 1, 2019
From: MIDCAP FUNDING X TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST), AS EXISTING ADMINISTRATIVE AGENT
To: MIDCAP FUNDING IV TRUST, AS SUCCESSOR TO EXISTING ADMINISTRATIVE AGENT
Reel/Frame 048481/0804 →
SECURITY INTEREST Recorded Dec 19, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FINANCIAL TRUST
Reel/Frame 044910/0685 →
SECURITY INTEREST Recorded Jun 15, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
Reel/Frame 042826/0358 →
RELEASE OF SECURITY INTEREST Recorded Jun 15, 2017
From: CERBERUS BUSINESS FINANCE, LLC. AS COLLATERAL AGENT
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 042821/0580 →
ASSIGNMENT FOR SECURITY - PATENTS Recorded Jan 13, 2016
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT
Reel/Frame 037513/0170 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2013
From: SOBERING, GEOFF; SCHNARR, ERIC; RUCHALA, KENNETH J.
To: TOMOTHERAPY INCORPORATED
Reel/Frame 029647/0042 →