IP Library › Patent Application 13742189
Patent Application
App. No. 13/742,189

MAMMALIAN CELL SURFACE ANTIGENS; RELATED REAGENTS

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Quick Facts
Patent No.
US None
App. No.
13/742,189
Abstract

Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen are provided. Methods of using said reagents and diagnostic kits are also provided.

Claims (8)

1 - 22 . (canceled)

23 . A substantially pure polypeptide comprising an extracellular domain of SEQ ID NO:4.

24 . The polypeptide of claim 23 , wherein the polypeptide is conjugated to a chemical moiety.

25 . The polypeptide of claim 23 , wherein the polypeptide is fused to a heterologous protein.

26 . The polypeptide of claim 25 , wherein the heterologous protein is selected from the group consisting of luciferase, bacterial β-galactosidase, trpE, Protein A, β-lactamase, alpha amylase, alcohol dehydrogenase, yeast alpha mating factor, and His 6 (SEQ ID NO:8).

27 . A pharmaceutical formulation comprising the polypeptide of claim 23 and a pharmaceutically and physiologically acceptable carrier.

28 . A substantially pure polypeptide comprising the amino acid sequence of SEQ ID NO:4.

29 . A pharmaceutical formulation comprising the polypeptide of claim 28 and a pharmaceutically and physiologically acceptable carrier.