Tissue transfer systems
View Patent ↗Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented.
1. A method of implanting tissue, comprising:
inserting a cannula percutaneously into a targeted area;
operating a pump including a pumping chamber to inject a plurality of aliquots of adipose tissue from a tissue reservoir through the cannula; and
injecting the plurality of aliquots of adipose tissue from the tissue reservoir through the cannula into each tract while withdrawing the cannula along a tract;
the injecting step comprising injecting a total of 100-1000 cc of adipose tissue into the targeted area from the reservoir;
wherein the pumping chamber defines a bore diameter and a priming bore diameter, the bore diameter separating the priming bore diameter from the cannula, the priming bore diameter being disposed at a proximal portion of the pumping chamber, and the priming bore diameter being dimensioned greater than the bore diameter of the pumping chamber; and
wherein the pumping chamber includes an opening formed in a wall of the pumping chamber at the priming bore diameter configured for ejection of air or debris from the pumping chamber.
2. The method of claim 1 , wherein each aliquot has a volume between 0.2 cc and 1.0 cc.
3. The method of claim 1 , wherein the targeted area is a female breast.
4. The method of claim 1 , further comprising visually observing a quantity of adipose tissue remaining in the reservoir.
5. The method of claim 1 , wherein the pump is a motorized pump, and wherein the injecting step comprises actuating the motorized pump.
6. The method of claim 5 , wherein the pump comprises a piston pump.
7. The method of claim 5 , wherein the cannula and the reservoir are supported by a handle, the actuating step comprising operating an actuator supported by the handle.
8. The method of claim 1 , further comprising monitoring a pump parameter during the injecting step.
9. The method of claim 8 , wherein the pump parameter is pump piston position.
10. The method of claim 8 , wherein the pump parameter is system pressure.
11. The method of claim 8 , further comprising notifying a user of a possible clog based on the monitored pump parameter.
12. The method of claim 1 , comprising positioning a plunger of the pump in a primed position to allow the air or debris to escape through the opening associated with the priming bore diameter of the pumping chamber.
13. A method of implanting tissue, comprising:
inserting a cannula percutaneously along a tract into a targeted area; and
operating a pump including a pumping chamber to inject a plurality of aliquots of adipose tissue from a tissue reservoir through the cannula into the tract at a pressure between 15 in Hg of vacuum and 51 in Hg of pressure;
wherein the pumping chamber defines a bore diameter and a priming bore diameter, the bore diameter separating the priming bore diameter from the cannula, the priming bore diameter being disposed at a proximal portion of the pumping chamber, and the priming bore diameter being dimensioned greater than the bore diameter of the pumping chamber; and
wherein the pumping chamber includes an opening formed in a wall of the pumping chamber at the priming bore diameter configured for ejection of air or debris from the pumping chamber.
14. The method of claim 13 , wherein the aliquots comprise aliquots of a first volume, the method further comprising changing the pump operation to inject a plurality of aliquots of a second volume, the second volume being different than the first volume.
15. The method of claim 14 , wherein the aliquot volumes are between 0.2 cc and 1.0 cc.
16. The method of claim 13 , comprising monitoring a pump parameter to identify a pump malfunction or a system clog.
17. The method of claim 16 , wherein the pump parameter is pump piston position.
18. The method of claim 16 , wherein the pump parameter is system pressure.
19. The method of claim 18 , further comprising notifying a user of a possible clog based on the monitored pump parameter.
20. A device for implanting tissue, comprising:
a handle comprising first and second longitudinally extending gripping surfaces adapted to be held by a user;
an injection cannula extending longitudinally from a cannula connection point in the handle, the cannula connection point being disposed below and distal to the first and second longitudinally extending gripping surfaces, the cannula being adapted to be inserted into a targeted area of a human body;
an adipose tissue reservoir connected to the handle; and
a pump including a pumping chamber disposed in the handle and adapted to pump a plurality of aliquots of adipose tissue from the adipose tissue reservoir into the cannula for delivery into the targeted area;
wherein the pumping chamber defines a bore diameter and a priming bore diameter, the bore diameter separating the priming bore diameter from the cannula, the priming bore diameter being disposed at a proximal portion of the pumping chamber, and the priming bore diameter being dimensioned greater than the bore diameter of the pumping chamber; and
wherein the pumping chamber includes an opening formed in a wall of the pumping chamber at the priming bore diameter configured for ejection of air or debris from the pumping chamber.
21. The system of claim 20 , further comprising a cannula coupler adapted to detachably couple the cannula to the handle.
22. The system of claim 20 , wherein the cannula connection point is disposed in an attachment assembly offset from the handle.
23. The system of claim 22 , wherein the attachment assembly comprises a control surface on a proximal portion adapted to receive pressure from a user's finger for leverage in pushing the system in a distal direction.
24. The system of claim 20 , wherein the reservoir is disposed above the gripping surfaces.
25. The system of claim 24 , wherein the reservoir is adapted to provide visual feedback with respect to a tissue volume remaining within the reservoir during an injection procedure.
26. The system of claim 24 , wherein the handle further comprises a control surface disposed between the first gripping surface and the reservoir adapted to receive a user's webbing between the user's thumb and forefinger.
27. The system of claim 20 , further comprising a pump actuator supported by the handle and disposed distal to the gripping surfaces and proximal to the cannula.
28. The system of claim 27 , wherein the first gripping surface is on a top side of the handle, pump actuator is disposed below the first gripping surface.
29. The system of claim 28 , wherein the second gripping surface is on a bottom side of the handle, the handle further comprising a guard extending downward from the second gripping surface and adapted to prevent inadvertent actuation of the pump actuator.
30. The system of claim 20 , further comprising a tissue flow path from the pump to the cannula, the tissue flow path comprising a channel extending in a downward angle from an outlet of the pump to an inlet of the cannula.
31. The system of claim 20 , wherein the pump comprises first and second chambers and a translatable plunger slideable therethrough.
32. The system of claim 20 , wherein the pump is adapted to deliver an aliquot of adipose tissue to the cannula, the system further comprising a controller configured to change the volume of the aliquot to be delivered.
33. The system of claim 32 , wherein the aliquot volume is between 0.2 cc and 1.0 cc.