Granted Patent
B2
US 8,921,350 · App. 13/743,166 · Granted Dec 30, 2014
Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
Inventors:
Xin Chen (San Ramon, CA); Peng Cheng (Union City, CA); L. Edward Clemens (Davis, CA); Jeffrey D. Johnson (Moraga, CA); Jingyuan Ma (Sunnyvale, CA); Alison Murphy (Milpitas, CA); Imad Nashashibi (San Jose, CA); Christopher J. Rabbat (San Jose, CA); Jiangao Song (Sunnyvale, CA); Maria E. Wilson (San Francisco, CA); Yan Zhu (Foster City, CA); Zuchun Zhao (Pleasanton, CA)
Assignee:
CymaBay Therapeutics, Inc.
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Abstract
Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
Claims (6)
1. A compound selected from the group consisting of:
or a salt thereof.
2. A compound of formula:
or a salt thereof.
3. A pharmaceutical composition comprising a compound of claim 1 .
4. A pharmaceutical composition comprising a compound of claim 2 .
Assignments (4)
RELEASE OF SECURITY INTEREST
Recorded Aug 7, 2015
From: SILICON VALLEY BANK; OXFORD FINANCE LLC
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 036307/0406 →
SECURITY AGREEMENT
Recorded Nov 22, 2013
From: CYMABAY THERAPEUTICS, INC.
To: SILICON VALLEY BANK; OXFORD FINANCE LLC
Reel/Frame 031710/0508 →
CHANGE OF NAME
Recorded Oct 22, 2013
From: METABOLEX, INC.
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 031475/0472 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 16, 2013
From: CHEN, XIN; CHENG, PENG; CLEMENS, L. EDWARD; JOHNSON, JEFFREY D.; MA, JINGYUAN; MURPHY, ALISON; NASHASHIBI, IMAD; RABBAT, CHRISTOPHER J.; SONG, JIANGAO; WILSON, MARIA E.; ZHU, YAN; ZHAO, ZUCHUN
To: METABOLEX, INC.
Reel/Frame 029644/0166 →
Continuity (5)
Provisional Application
60877903
· Dec 28, 2006