METHOD AND SYSTEM FOR TISSUE FASTENING
Fastening devices are provided that are designed to effectively close tissue as well as instruments for applying the inventive fastening devices. The devices are useful for closing tissue such as mucosa in the oral cavity, oropharynx, hypopharynx, laryngeal surfaces, oronasopharynx, or other mucosal tissues. In particular, uvulopalatopharyngoplasty (UPPP), uvulopalatal flap (UPF) technique, and tonsillectomy can be assisted using the inventive system. Embodiments also provide methods of using the fastening devices and/or instruments, and kits including the fastening devices.
1 .- 10 . (canceled)
11 . A method of fastening tissue, the method comprising:
providing a fastening device comprising a body having a male fastening member disposed on a first end of the body, a female fastening member configured to receive the male fastening member in a locked configuration and disposed on a second end of the body, wherein the fastening device forms a closed structure when the male and female fastening members are in the locked configuration;
retracting a portion of uvulopalatal tissue towards a portion of soft palate tissue;
piercing the uvulopalatal tissue and soft palate tissue; and
securing the male fastening member with the female fastening member such that the fastening device maintains an approximation of the uvulopalatal tissue and the soft palate tissue.
12 . The method of claim 11 , further comprising:
crimping the body after piercing the uvulopalatal tissue and the soft palate tissue.
13 . The method of claim 11 , wherein the fastening device is included in a cassette of multiple fastening devices.
14 . The method of claim 11 , further comprising:
utilizing an instrument to place the fastening device in a desired location; and
actuating the instrument to cause the first fastening member to pierce the uvulopalatal tissue.
15 . The method of claim 11 , wherein the steps are performed in the context of a uvulopalatopharyngoplasty (UPPP) with or without tonsillectomy procedure.
16 . The method of claim 11 , wherein the steps are performed in the context of a tonsillectomy procedure.
17 . The method of claim 11 , wherein the steps are performed in the context of a uvulopalatal flap (UPF) procedure.
18 . A method of fastening tissue in a uvulopalatal tissue procedure, the method comprising:
providing a fastening device comprising a body having a male fastening member disposed on a first end of the body, a female fastening member configured to couple to the male fastening member and disposed on a second end of the body, wherein the fastening device forms a closed structure when the male and female fastening members are in a locked configuration;
locating the fastening device proximal to a portion of uvulopalatal tissue and a portion of soft palate tissue;
retracting the uvulopalatal tissue towards the soft palate tissue;
piercing the portion of uvulopalatal tissue and portion of soft palate tissue; and
coupling the male fastening member to the female fastening member.
19 . The method of claim 18 , wherein the fastening device comprises a substantially flat surface that engages the portion of uvulopalatal tissue and the portion of soft palate tissue.
20 . The method of claim 18 , wherein the fastening device is included in a cassette of multiple fastening devices.
21 . The method of claim 18 , further comprising:
utilizing an instrument to place the fastening device in a desired location; and
actuating the instrument to cause the first fastening member to pierce the uvulopalatal tissue.
22 . The method of claim 18 , wherein the male fastening member comprises a sharp point and the female fastening member comprises an aperture configured to receive the male fastening member.
23 . The method of claim 18 , wherein the steps are performed in the context of a uvulopalatopharyngoplasty (UPPP) with tonsillectomy procedure.
24 . The method of claim 18 , wherein the steps are performed in the context of a tonsillectomy procedure.
25 . (canceled)
26 . A fastening device for securing uvulopalatal tissue, comprising:
a body formed of two arc-shaped segments having a first end and a second end and having an interior surface directed towards the center of the body, wherein the interior surface is substantially flat, and an exterior surface directed away from the center of the body;
a hinged segment along the body about which the first end and second end are movable towards one another;
a male fastening member disposed on the first end of the body; and
a female fastening member disposed on the second end of the body, wherein the female fastening member is configured to receive the male fastening member into a locked configuration such that the fastening device forms a closed structure when the male and female fastening members are in the locked configuration,
wherein the arc-shaped segments extend from the hinged segment and are sized for placement around uvulopalatal tissue of a subject.
27 . The device of claim 26 wherein the male fastening member is tapered for piercing tissue.
28 . The device of claim 26 wherein the male fastening member comprises a barbed shape.
29 . The device of claim 26 wherein the body defines a partial circle.
30 . The device of claim 26 wherein the device is comprised of a biocompatible, bioresorbable material.
31 . The device of claim 26 wherein the device is coated with a protein or growth factor-based product to enhance healing of the tissue during use.
32 . The device of claim 26 wherein the female fastening member comprises at least one of a hole, an aperture, or a cavity for receiving the male fastening member.
33 . The device of claim 32 wherein the male fastening member comprises at least one of a flange or swelling for locking into the at least one of a hole, an aperture, or a cavity of the female fastening member.