IP Library Granted Patent US 8,790,293
Granted Patent B2
US 8,790,293 · App. 13/763,587 · Granted Jul 29, 2014

Injector apparatus with fixed plunger and method of use

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Quick Facts
Patent No.
US 8,790,293
App. No.
13/763,587
Granted
Jul 29, 2014
Kind
B2
Abstract

Disclosed herein is an injector device for delivering an implant, the device including a retracting element, a cannula needle, and a plunger. The device may comprise an latch that, when actuated by a user, causes the retracting element to move the cannula needle away from the delivery site, allowing the plunger to eject the implant into the site. The device may be configured for intraocular drug delivery.

Claims (24)

1. An injector device comprising:

a syringe barrel defining a central axial cavity, and having a distal end and a proximal end;

a cannula needle having a distal end and a proximal end and defining a central axial cavity in communication with the central axial cavity of the syringe barrel;

a retracting element coaxially coupled to the proximal end of the cannula needle adapted to retract the cannula needle into the syringe barrel;

a plunger having a distal end and a proximal end, disposed in the central axial cavity of the syringe barrel at a fixed position therein, and, when the cannula needle retracts, extending through the central axial cavity of the cannula needle and beyond the distal end of the syringe barrel; and

an implant disposed in the central axial cavity of the cannula needle between the plunger rod and the distal end of the needle.

2. The injector according to claim 1 , wherein the device further comprises a disengageable block that obstructs the implant from exiting the distal end of the cannula needle.

3. The injector according to claim 1 , further comprising a latch located on the exterior of the syringe barrel and coupled to the retracting element such that when the latch is activated, the cannula needle retracts.

4. The injector according to claim 1 , further comprising a stop disposed on the cannula needle and having a portion that extends beyond a cross section of the cannula needle.

5. The injector of claim 4 , wherein the stop includes a tubular collar coaxially positioned with the cannula needle, and a positive cross-sectional area difference between the tubular collar and the needle prevents penetration of the cannula needle into a tissue beyond a pre-determined depth.

6. The injector according to claim 1 , further comprising one or more anchor elements at the proximal end of the plunger to hold the plunger in place.

7. The injector according to claim 3 , further comprising a disengageable latch guard coupled to the latch to prevent activation of the latch while the latch guard is engaged.

8. The injector according to claim 2 , wherein the block is a wire having a hook shape, and a first bell-shaped end of the wire caps the distal end of the cannula needle and a second end of the wire is secured to a portion of the injector device.

9. A method of injecting an implant using an injector device, comprising:

providing an injector device of claim 3 ;

inserting the cannula needle into a tissue;

activating the latch to cause the retracting element to retract the cannula needle from around the implant; and

removing the device from the tissue while leaving the implant in the tissue.

10. The method of claim 9 , wherein the tissue is an eye.

11. The method of claim 9 , wherein the cannula needle is a 25-gauge needle.

12. The method of claim 9 , wherein the cannula needle has a beveled tip adapted to penetrate a sclera of an eye.

13. The method according to claim 9 , wherein a longitudinal length of the implant is between 0.1 to 0.6 centimeters.

14. The method of claim 9 , wherein the device further comprises a stop disposed on the cannula needle, the stop having a portion that extends beyond a cross section of the cannula needle, whereby the insertion of the cannula needle into the tissue is stopped when a surface of the tissue contacts the stop.

15. The method of claim 9 , wherein the device further comprises a disengageable block that obstructs the implant from exiting the distal end of the cannula needle, and wherein the method further comprises disengaging the block from the injector device prior to inserting the cannula needle into the tissue.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Mar 14, 2022
From: CRG SERVICING LLC, AS ADMINISTRATIVE AGENT
To: EYEPOINT PHARMACEUTICALS, INC.; EYEPOINT PHARMACEUTICALS US, INC.; ICON BIOSCIENCE, INC.
Reel/Frame 059365/0112 →
CHANGE OF NAME Recorded Apr 2, 2019
From: PSIVIDA US, INC.
To: EYEPOINT PHARMACEUTICALS, INC.
Reel/Frame 049108/0700 →
SECURITY INTEREST Recorded Feb 13, 2019
From: EYEPOINT PHARMACEUTICALS, INC.; EYEPOINT PHARMACEUTICALS US, INC.; ICON BIOSCIENCE, INC.
To: CRG SERVICING LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 048329/0045 →
RELEASE OF SECURITY INTEREST Recorded Feb 13, 2019
From: SWK FUNDING LLC, AS AGENT
To: PSIVIDA CORP.; PSIVIDA US, INC.; ICON BIOSCIENCE, INC.
Reel/Frame 048329/0136 →
SECURITY INTEREST Recorded Apr 5, 2018
From: PSIVIDA CORP.
To: SWK FUNDING LLC, AS AGENT
Reel/Frame 045848/0670 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2014
From: NAZZARO, MARTIN; YORK, JOSH; LEBLANC, RON
To: PSIVIDA US, INC.
Reel/Frame 032183/0591 →