IP Library › Granted Patent US 9,193,749
Granted Patent B2
US 9,193,749 · App. 13/767,478 · Granted Nov 24, 2015

Dibenzo[b,f][1,4]oxazepin-11-yl-N-hydroxybenzamides as HDAC inhibitors

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Quick Facts
Patent No.
US 9,193,749
App. No.
13/767,478
Granted
Nov 24, 2015
Kind
B2
Abstract

This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I) wherein Q, J, L and Z are as defined in the specification.

Claims (4)

1. A method of inhibiting histone deacetylase, comprising contacting the histone deacetylase with a pharmaceutical composition comprising:

i) (Z)-4-(dibenzo[b,f][1,4]oxazepin-11-yl)-N-hydroxybenzamide, or a pharmaceutically acceptable salt thereof; and

ii) a pharmaceutically acceptable carrier, excipient, or diluent.

2. A method of inhibiting histone deacetylase, comprising contacting the histone deacetylase with (Z)-4-(dibenzo[b,f][1,4]oxazepin-11-yl)-N-hydroxybenzamide, or a pharmaceutically acceptable salt thereof.

Assignments (4)
SECURITY INTEREST Recorded Jul 5, 2016
From: FORUM PHARMACEUTICALS INC.
To: FMR LLC
Reel/Frame 039254/0828 →
CHANGE OF NAME Recorded Oct 29, 2014
From: ENVIVO PHARMACEUTICALS, INC.
To: FORUM PHARMACEUTICALS, INC.
Reel/Frame 034086/0947 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2014
From: SHAPIRO, GIDEON; CHESWORTH, RICHARD
To: ENVIVO PHARMACEUTICALS
Reel/Frame 032356/0327 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2014
From: DEZIEL, ROBERT; LEIT, SILVANNA; BEAULIEU, PATRICK; CHANTIGNY, YVES ANDRE; MANCUSO, JOHN; TESSIER, PIERRE; SMIL, DAVID
To: METHYLGENE INC.
Reel/Frame 032356/0479 →