A nasal delivery device and a method of delivering substance to a nasal airway of a subject can be used for mass treatment, especially mass vaccination. The delivery device can include an interface unit, as a replaceable unit, having at least one nosepiece unit for fitting to a respective nostril of a subject, a nozzle from which substance is in use delivered, and at least one delivery unit having a substance supply unit for delivering substance to the nozzle of the at least one nosepiece unit. The delivery device can also include an actuation unit for actuating the at least one delivery unit of the interface unit.
1. A nasal delivery device for delivering substance to a nasal airway of a subject, comprising:
a plurality of interface units attached to one another via a common support, each interface unit being a single integral unit and comprising:
(i) at least one nosepiece unit for fitting to a respective nostril of a subject and including a nozzle from which substance is in use delivered, and
(ii) at least one delivery unit comprising a substance supply unit for delivering substance to the nozzle of the at least one nosepiece suit; and
an actuation unit to which the plurality of interface units are successively attached for actuating the at least one delivery unit of each respective interface unit, the actuation unit being configured to receive the at least one delivery unit in a position to be actuated to deliver substance to the nozzle, wherein the actuation unit is configured to be actuated in response to exhalation by the subject.
2. The delivery device of claim 1 , wherein the common support is a belt.
3. The delivery device of claim 2 , wherein the plurality of interface units attached to the belt are advanceable so as to be successively aligned with the actuation unit.
4. The delivery device of claim 1 , wherein each interface unit further comprises a mouthpiece.
5. The delivery device of claim 4 , wherein the mouthpiece and nosepiece of each interface unit are fluidly connected such as to provide an air flow through the nosepiece on exhalation by the subject into the mouthpiece.
6. The delivery device of claim 4 , wherein each interface unit further comprises a pressure sensor.
7. The delivery device of claim 1 , wherein the substance comprises a powder.
8. The delivery device of claim 1 , wherein the substance comprises a liquid.