MODALITY WORK LIST SYSTEM
Methods and systems for automatically and dynamically determining a dose of a radiopharmaceutical are disclosed. The dose may be determined based on, among other things, radiopharmaceutical information associated with at least one source of a radiopharmaceutical, patient information and schedule information. An estimated radioactivity level may be determined based on an initial radioactivity level, a delivery time, a radioactivity decay rate, and an anticipated arrival time. A volume of the radiopharmaceutical to inject into a patient to deliver a dose of radioactivity may be determined based on the estimated radioactivity level and patient dosing information. An infusion apparatus may operate to inject the patient with the volume of the radiopharmaceutical.
1 . A system for determining a dose of a radiopharmaceutical, the system comprising:
a processor; and
one or more non-transitory, computer-readable storage mediums containing:
radiopharmaceutical information associated with at least one source of a radiopharmaceutical, the radiopharmaceutical information comprising an initial radioactivity level, a radioactivity decay rate and a delivery time,
patient information comprising a patient identifier and patient dosing information, and
schedule information comprising an anticipated arrival time,
wherein at least one of the one or more computer-readable storage mediums is in operable communication with the processor and contains one or more programming instructions that, when executed, cause the processor to:
determine an estimated radioactivity level based on the initial radioactivity level, the delivery time, the radioactivity decay rate, and the anticipated arrival time, and
determine a volume of the radiopharmaceutical to inject into a patient to deliver a dose of radioactivity based on the estimated radioactivity level and the patient dosing information.
2 . The system of claim 1 , wherein the radiopharmaceutical comprises one of the following: 64 Cu diacetyl-bis(N4-methylthiosemicarbazone), 18 F-fluorodeoxyglucose (FDG), 18 F-fluoride, 3′-deoxy-3′-[ 18 F]fluorothymidine, 18 F-fluoromisonidazole, gallium, technetium-99m ( 99m Tc), indium-113m ( 113m In), strontium-87m ( 87m Sr), and thallium.
3 . The system of claim 1 , wherein the initial radioactivity level comprises a radioactivity of the source of the pharmaceutical at the delivery time.
4 . The system of claim 1 , wherein the delivery time comprises a time that the radiopharmaceutical was delivered.
5 . The system of claim 1 , wherein the delivery time comprises a time that the radiopharmaceutical was formulated.
6 . The system of claim 1 , wherein the radioactivity decay rate comprises a half-life of the radiopharmaceutical.
7 . The system of claim 1 , wherein the patient dosing information comprises a dose of radioactivity of the radiopharmaceutical.
8 . The system of claim 1 , wherein the radiopharmaceutical information further comprises a remaining volume of the at least one source of the radiopharmaceutical that is calculated by subtracting the volume from a current volume of the at least one source of the radiopharmaceutical.
9 . A method for determining a dose of a radiopharmaceutical, the method comprising:
receiving, for storage in one or more non-transitory, computer-readable storage mediums:
radiopharmaceutical information associated with at least one volume of a radiopharmaceutical, the radiopharmaceutical information comprising an initial radioactivity level, a radioactivity decay rate and a delivery time,
patient information comprising a patient identifier and patient dosing information, and
schedule information comprising an anticipated arrival time,
determining, by a processor in operable communication with the one or more non-transitory, computer-readable storage mediums, an estimated radioactivity level of a radiopharmaceutical based on the initial radioactivity level, the delivery time, the radioactivity decay rate, and the anticipated arrival time; and
determining, by the processor, a volume of the radiopharmaceutical to inject into a patient to deliver a dose of radioactivity based on the estimated radioactivity level and the patient dosing information.
10 . The method of claim 9 , wherein the initial radioactivity level comprises a radioactivity of the source of the pharmaceutical at the delivery time.
11 . The method of claim 9 , wherein the delivery time comprises a time that the radiopharmaceutical was delivered.
12 . The method of claim 9 , wherein the delivery time comprises a time that the radiopharmaceutical was formulated.
13 . The method of claim 9 , wherein the radioactivity decay rate comprises a half-life of the radiopharmaceutical.
14 . The method of claim 9 , wherein the patient dosing information comprises a dose of radioactivity of the radiopharmaceutical.
15 . The method of claim 9 , further comprising calculating a remaining volume of the at least one source of the radiopharmaceutical by subtracting the volume from a current volume of the at least one source of the radiopharmaceutical.
16 . The method of claim 15 , further comprising monitoring the remaining volume.
17 . The method of claim 15 , further comprising updating the remaining volume responsive to determining the volume.
18 . The method of claim 15 , further comprising generating an alarm responsive to the volume being greater than the remaining volume.
19 . The method of claim 9 , further comprising presenting a radiopharmaceutical dose user interface on at least one display device in operable communication with the processor, the radiopharmaceutical dose user interface being configured to present the patient identifier, the patient dosing information and the volume.
20 . The method of claim 19 , further comprising configuring an infusion apparatus in operable communication with the processor to use the volume as an injection volume of the radiopharmaceutical to inject into the patient responsive to selection of the accept function.