Granted Patent
B2
US 9,290,742 · App. 13/799,520 · Granted Mar 22, 2016
Tissue engineered blood vessel
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Abstract
Compositions and methods of using tissue engineered blood vessels to repair and regenerate blood vessels of patients with vascular disease are disclosed.
Claims (6)
1. A method of making a tissue engineered blood vessel comprising the steps of:
a. Providing a scaffold comprising a solution of poly(p-dioxanone) and 1,1,1,3,3,3-hexafluoro-2-propanol solvent formed as an electrospun tubular scaffold of randomly oriented fibers;
b. Cutting the electrospun tubular scaffold to form a scaffold sheet;
c. Seeding said scaffold sheet with cells;
d. Rolling said seeded sheet into a tube; and
e. Culturing the tube in a bioreactor.
Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 1, 2025
From: CARDINAL HEALTH SWITZERLAND 515 GMBH; CARDINAL HEALTH 529, LLC; CORDIS CORPORATION; FLEXIBLE STENTING SOLUTIONS, INC
To: CORDIS US CORP
Reel/Frame 072987/0675 →
SECURITY INTEREST
Recorded Oct 1, 2025
From: CORDIS US CORP.; ACCESS CLOSURE, LLC
To: HPS INVESTMENT PARTNERS, LLC
Reel/Frame 072973/0157 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 27, 2017
From: CORDIS CORPORATION
To: CARDINAL HEALTH SWITZERLAND 515 GMBH
Reel/Frame 042169/0662 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 24, 2017
From: ETHICON, INC.
To: CORDIS CORPORATION
Reel/Frame 042123/0247 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 20, 2017
From: COOPER, KEVIN; CHUN, IKSOO; COLTER, DAVID C; DHANARAJ, SRIDEVI; GOSIEWSKA, ANNA; SEYDA, AGNIESZKA; FANG, CARRIE H.; YANG, CHUNLIN
To: ETHICON, INC.
Reel/Frame 042078/0469 →