IP Library › Granted Patent US 8,636,994
Granted Patent B2
US 8,636,994 · App. 13/800,138 · Granted Jan 28, 2014

Polymer-based compositions and conjugates of antimicrobial agents

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Quick Facts
Patent No.
US 8,636,994
App. No.
13/800,138
Granted
Jan 28, 2014
Kind
B2
Abstract

Provided herein are water-soluble polymer conjugates and polymer-based compositions of antimicrobial agents. Also provided are methods for synthesizing and administering such conjugates and compositions.

Claims (6)

1. A pharmaceutical composition comprising:

(i) a conjugate selected from the group consisting of

wherein, in each case, (LY) is a residue of lysostaphin, k is one, and (n) is defined to provide a weight average molecular weight from about 5,000 Daltons to about 85,000 Daltons, and

(ii) a pharmaceutically acceptable excipient.

2. The pharmaceutical composition of claim 1 , wherein the weight average molecular weight is from about 15,000 Daltons to about 40,000 Daltons.

3. The pharmaceutical composition of claim 2 , wherein the weight average molecular weight is about 30,000 Daltons.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 31217, FRAME 0776 Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036876/0130 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
SECURITY AGREEMENT Recorded Sep 16, 2013
From: NEKTAR THERAPEUTICS
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 031217/0776 →