Methods and systems for automatically identifying detection parameters for an implantable medical device
View Patent ↗An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spiking, and power changes in the sensed signals, etc. A detection tool may be selected and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired.
1. A method for automatically deriving, through a computer, a parameter set for a detection tool implemented in an active medical device implantable in a patient for detecting electrographic activity, the method comprising:
receiving through a user interface coupled to the computer, an indication of at least one region of interest in a portion of a signal, the at least one region of interest having at least a starting point;
analyzing the at least one region of interest via an activity type algorithm resident in the computer, to determine from among a plurality of different activity types, a determined activity type with which to characterize the at least one region of interest;
automatically selecting, via an algorithm resident in the computer, a type of a detection tool based on the determined activity type;
further analyzing the at least one region of interest via an algorithm resident in the computer, to automatically derive a set of operating parameters for the selected type of detection tool, the set of automatically-derived operating parameters and the selected type of detection tool defining an instance of a detection tool; and
displaying a simulation through the user interface, the simulation corresponding to the electrographic activity the instance of the detection tool is likely to detect.
2. The method of claim 1 , further comprising:
establishing an order of parameters or combinations of parameters within the set of automatically-derived operating parameters that corresponds to the determined activity type;
based on input from the user, adjusting one or more values in the set of automatically-derived operating parameters in the established order; and
displaying a refreshed simulation through the user interface, the simulation corresponding to the electrographic activity the detection tool is likely to detect with the adjusted one or more values.
3. The method of claim 1 wherein the determined activity type is one of rhythmic activity, spiking activity, a combination of rhythmic activity and spiking activity, and a change in power of the signal relative to a predetermined power level.
4. The method of claim 1 wherein the type of detection tool for the determined activity type is one of a half wave detector, a line length detector, and an area detector.
5. The method of claim 1 wherein the portion of a signal is a portion of an electrographic signal previously acquired from the patient, the determined activity type is rhythmic activity, the type of detection tool is a half wave detector, and the set of automatically-derived operating parameters for the instance of the half wave detector is a half wave hysteresis parameter, a minimum half wave amplitude parameter, a minimum half wave width parameter, a half wave count criterion parameter, a half wave window size parameter, a qualified analysis window count parameter, and a detection analysis window size parameter.
6. The method of claim 5 wherein further analyzing the at least one region of interest to automatically deriving a set of operating parameters for the selected type of detection tool further comprises:
based on a content of the at least one region of interest, determining a value corresponding to at least one peak frequency; determining a value for the half wave window size parameter, determining a value for the half wave count criterion parameter, determining a value for the minimum half wave width parameter, determining a value for the half wave hysteresis parameter, determining a value for the minimum half wave amplitude parameter, determining a value for the detection analysis window size parameter and the qualified analysis window count; and
displaying a simulation through the user interface, the simulation corresponding to the rhythmic activity the instance of the half wave detector is likely to detect with the set of automatically-derived operating parameters.
7. The method of claim 6 further comprising:
based on a graphical content of the at least one region of interest, establishing an order of parameters in the set of automatically-derived operating parameters;
based on input from the user, adjusting the value of one or more of the parameters in the set of automatically-derived operating parameters so that the instance of the half wave detector is biased to detect more or less of the graphical content; and
if any adjustments to the value of any parameters in the set of automatically-derived operating parameters have been made, displaying a refreshed simulation through the user interface, the simulation corresponding to the rhythmic activity the instance of the half wave detector is likely to detect with the adjustments.
8. The method of claim 1 wherein the portion of a signal is a portion of an electrographic signal previously acquired from the patient, the determined activity type is spiking activity, the type of detection tool is a half wave detector, and the set of automatically-derived operating parameters for the instance of the half wave detector is a half wave hysteresis parameter, a minimum half wave amplitude parameter, a minimum half wave width parameter, a half wave count criterion parameter, a half wave window size parameter, a qualified analysis window count parameter, and a detection analysis window size parameter.
9. The method of claim 8 wherein further analyzing the at least one region of interest to automatically derive a set of operating parameters for the selected type of detection tool further comprises:
based on the content of the at least one region of interest, determining a value for the half wave hysteresis parameter; determining a value for the minimum half wave amplitude parameter, determining a value for the minimum half wave width parameter, determining a value for the half wave window size parameter and the half wave count criterion parameter, and determining a value for the detection analysis window size parameter and the qualified analysis window count parameter; and
displaying a simulation through the user interface, the simulation corresponding to the spiking activity the instance of the half wave detector is likely to detect with the set of automatically-derived operating parameters.
10. The method of claim 9 further comprising:
based on input from a user, adjusting the value of one or more of the parameters in the set of automatically-derived operating parameters so that the amplitude corresponding to the amplitude of the spiking activity the instance of the half wave detector is likely to detect with the set of automatically-derived operating parameters is modified; and
displaying a refreshed simulation through the user interface, the simulation corresponding to the spiking activity the instance of the half wave detector is likely to detect with the adjusted value.
11. The method of claim 1 wherein the portion of a signal is a portion of an electrographic signal previously acquired from the patient, the determined activity type is an activity corresponding to a change in power of the signal compared to a predetermined norm, the type of detection tool is a line length detector, and the set of automatically-derived operating parameters for the instance of the line length detector is a short term window size parameter, a long term window size parameter, a detection threshold parameter, a threshold logic parameter, a threshold mode parameter, a sample count parameter, an inter-sample interval parameter, and a persistence parameter.
12. The method of claim 11 , further comprising:
adjusting a value in the set of automatically-derived operating parameters based on input from the user; and
displaying a refreshed simulation through the user interface, the simulation corresponding to the power change activity the instance of the line length detector is likely to detect with the adjusted value.
13. The method of claim 1 wherein the determined activity type is one of rhythmic activity, spiking activity, a combination of rhythmic activity and spiking activity, and a change in power of the signal relative to a predetermined power level, and the method further comprising selecting an instance of a default detection tool with a predetermined set of operating parameters if analyzing the at least one region of interest to determine at least one activity type with which to characterize the at least one region of interest is unsuccessful.
14. A method for automatically deriving, through a computer, a parameter set for a detection tool implemented in an active medical device implantable in a patient for detecting electrographic activity, the method comprising:
receiving through a user interface coupled to the computer, indications of two or more regions of interest in a portion of a signal, each of the two or more regions of interest having a starting point and an ending point;
determining, via an algorithm resident in the computer, whether to combine a plurality of the two or more regions of interest, and, if a determination to combine is made, eliciting input from a user as to whether the combination should be undertaken, and if the input indicates that the combination should be undertaken, then:
analyzing the combined regions of interest via an activity type algorithm resident in the computer, to determine from among a plurality of different activity types, a determined activity type with which to characterize the combined regions of interest;
automatically selecting, via an algorithm resident in the computer, a type of a detection tool based on the determined activity type;
further analyzing the combined regions of interest via an algorithm resident in the computer, to automatically derive a set of operating parameters for the selected type of detection tool, the set of automatically-derived operating parameters and the selected type of detection tool defining an instance of a detection tool; and
displaying a simulation through the user interface, the simulation corresponding to the electrographic activity the instance of the detection tool is likely to detect.
15. The method of claim 14 further comprising automatically deriving a set of operating parameters for a power change detection tool if the input indicates that the combination should not be undertaken.