Impeller for catheter pump
An impeller for a pump is disclosed herein. The impeller can include a hub having a fixed end and a free end. The impeller can also have a plurality of blades supported by the hub. Each blade can have a fixed end coupled to the hub and a free end. The impeller can have a stored configuration and a deployed configuration, the blades in the deployed configuration extending away from the hub, and the blades in the stored configuration being compressed against the hub.
1. A percutaneous heart pump system, the system comprising:
an impeller disposed at a distal portion of the system, the impeller sized and shaped to be inserted through a vascular system of a patient,
wherein the impeller is configured to pump blood through at least a portion of the vascular system at a flow rate of at least about 3.5 liters per minute when the impeller is rotated at a speed less than about 21,000 revolutions per minute.
2. The system of claim 1 , wherein the impeller is configured to pump blood through at least a portion of the vascular system at a flow rate of at least about 4.25 liters per minute when the impeller is rotated at a speed less than about 21,000 revolutions per minute.
3. The system of claim 2 , wherein the impeller is configured to pump blood through at least a portion of the vascular system at a flow rate of at least about 4.25 liters per minute when the impeller is rotated at a speed in a range of about 18,500 revolutions per minute to about 21,000 revolutions per minute.
4. The system of claim 3 , wherein the impeller is configured to pump blood through at least a portion of the vascular system at a flow rate in a range of about 4.25 liters per minute to about 5.5 liters per minute when the impeller is rotated at a speed in a range of about 18,500 revolutions per minute to about 21,000 revolutions per minute.
5. The system of claim 1 , wherein the impeller is configured to pump blood through at least a portion of the vascular system at a flow rate of at least about 3.5 liters per minute when a head pressure in the vascular system is at least about 60 mmHg and when the impeller is rotated at a speed less than about 21,000 revolutions per minute.
6. The system of claim 5 , wherein the impeller is configured to pump blood through at least a portion of the vascular system at a flow rate of at least about 3.5 liters per minute when a head pressure in the vascular system is about 62 mmHg and when the impeller is rotated at a speed less than about 21,000 revolutions per minute.
7. The system of claim 1 , further comprising a drive shaft operably coupled to the impeller and configured to rotationally drive the impeller.
8. The system of claim 1 , wherein an insertion diameter of the distal portion of the system has a catheter size of less than about 13 FR.
9. The system of claim 1 , wherein the impeller comprises a single blade row having one or more blades.
10. The system of claim 1 , wherein the impeller is an expandable impeller configured to expand from a stored configuration to an expanded configuration.
11. A method of pumping blood through the vascular system of a patient, the method comprising:
inserting an impeller through a portion of the vascular system of the patient to a heart chamber; and
rotating the impeller at a speed less than about 21,000 revolutions per minute to pump blood through at least a portion of the vascular system at a flow rate of at least about 3.5 liters per minute.
12. The method of claim 11 , further comprising rotating the impeller at a speed less than about 21,000 revolutions per minute to pump blood through at least a portion of the vascular system at a flow rate of at least about 4.25 liters per minute.
13. The method of claim 12 , further comprising rotating the impeller at a speed in a range of about 18,500 revolutions per minute to about 21,000 revolutions per minute to pump blood through at least a portion of the vascular system at a flow rate of at least about 4.25 liters per minute.
14. The method of claim 13 , further comprising rotating the impeller at a speed in a range of about 18,500 revolutions per minute to about 21,000 revolutions per minute to pump blood through at least a portion of the vascular system at a flow rate in a range of about 4.25 liters per minute to about 5.5 liters per minute.
15. The method of claim 11 , wherein, when rotating the impeller, a head pressure in the vascular system is at least about 60 mmHg.
16. An impeller configured for us in a catheter pump, the impeller comprising:
a hub having a distal portion, a proximal portion, and a diameter; and
a blade having a fixed end at the hub and a free end, the blade having a height defined by a maximum distance between the hub and the free end,
wherein a value relating to a ratio of the blade height to the hub diameter is in a range of about 0.7 to about 1.45.
17. The impeller of claim 16 , wherein the value relating to the ratio of the blade height to the hub diameter is in a range of about 0.7 to about 1.1.
18. The impeller of claim 17 , wherein the value relating to the ratio of the blade height to the hub diameter is in a range of about 0.75 to about 1.
19. The impeller of claim 16 , wherein the diameter of the hub is defined by a first diameter near the distal portion of the hub or a second diameter near the proximal portion of the hub.
20. The impeller of claim 16 , wherein the diameter of the hub is defined by an average of a first diameter near the distal portion of the hub and a second diameter near the proximal portion of the hub.
21. The impeller of claim 20 , wherein the first diameter is larger than the second diameter.
22. The impeller of claim 16 , wherein the impeller has a stored configuration and a deployed configuration, the value relating the ratio of the blade height to the hub diameter based on the deployed configuration.
23. The impeller of claim 22 , wherein the impeller is configured to self-deploy from the stored configuration to the deployed configuration.
24. The impeller of claim 22 , wherein the blade has a leading edge and a trailing edge, wherein a ramped surface is formed at the trailing edge of the blade, the ramped surface configured to bear against a sheath to urge the impeller into the stored configuration.
25. The impeller of claim 22 , wherein the impeller has a diameter in the stored configuration corresponding to a catheter size between about 8 FR and about 21 FR, and a diameter in the deployed configuration corresponding to a catheter size above about 12 FR.
26. The impeller of claim 25 , wherein the impeller has a diameter in the stored configuration corresponding to a catheter size between about 12 FR and about 21 FR, and a diameter in the deployed configuration corresponding to a catheter size above about 21 FR.
27. A percutaneous heart pump system, the system comprising:
an impeller disposed at a distal portion of the system, the impeller sized and shaped to be inserted into a vascular system of a patient through a percutaneous access site having a size less than about 21 FR,
wherein the impeller is configured to pump blood in the vascular system at a flow rate of at least about 3.5 liters per minute.
28. A percutaneous heart pump system, the system comprising:
an impeller comprising one or more blades in a single row, the impeller disposed at a distal portion of the system, the impeller sized and shaped to be inserted through a vascular system of a patient,
wherein the impeller is configured to pump blood through at least a portion of the vascular system at a flow rate of at least about 2.0 liters per minute when the impeller is rotated at a speed less than about 21,000 revolutions per minute.
29. The percutaneous heart pump system of claim 28 , wherein the blades are expandable.