IP Library Granted Patent US 8,948,854
Granted Patent B2
US 8,948,854 · App. 13/810,064 · Granted Feb 3, 2015

Non-invasive monitoring of physiological conditions

Inventors: Paul A. Friedman (Rochester, MN); Kevin E. Bennet (Rochester, MN); Charles J. Bruce (Rochester, MN); Virend K. Somers (Rochester, MN)
Assignee: Mayo Foundation for Medical Education and Research
A61B5/04525A61B5/14532A61B5/14546A61B5/0472
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,948,854
App. No.
13/810,064
Granted
Feb 3, 2015
Kind
B2
Abstract

This document provides methods and materials related to the non-invasive measurement of analytes in blood.

Claims (23)

1. A method for assessing the level of an analyte within a human, the method comprising:

generating, using a signal averaging technique, electrocardiogram results from said human; and

comparing said results to a signal template to obtain an indication of the level of said analyte in said human.

2. The method of claim 1 , further comprising generating, using the signal averaging technique, said signal template.

3. The method of claim 1 , wherein said signal template represents a level of analyte that is within the normal human physiologic range of levels for said analyte.

4. The method of claim 1 , wherein said signal template represents a level of analyte that is outside the normal human physiologic range of levels for said analyte.

5. The method of claim 1 , wherein said electrocardiogram results, when compared to said signal template, indicate that the level of said analyte in said human is within said normal human physiologic range of levels for said analyte.

6. The method of claim 1 , wherein said electrocardiogram results, when compared to said signal template, indicate that the level of said analyte in said human is outside said normal human physiologic range of levels for said analyte.

7. A method for assessing a change in the level of an analyte within a human as compared to a previously determined level of said analyte, wherein said method comprises:

(a) generating, using a signal averaging technique, electrocardiogram results from said human,

(b) comparing said results to a signal template to obtain an indication of the level of said analyte in said human, and

(c) comparing the level of said analyte in said human to said previously determined level of said analyte to determine a change, wherein said change is a change that is not detectable based on visual inspection of an ECG tracing.

8. The method of claim 7 , wherein said change is less than 25 percent of the normal physiologic range of said analyte.

9. The method of claim 7 , wherein said change is less than 20 percent of the normal physiologic range of said analyte.

10. The method of claim 7 , wherein said change is less than 15 percent of the normal physiologic range of said analyte.

11. The method of claim 7 , wherein said change is less than 10 percent of the normal physiologic range of said analyte.

12. The method of claim 7 , wherein said change is less than 5 percent of the normal physiologic range of said analyte.

13. A method for assessing a change in the level of an analyte within a human as compared to a previously determined level of said analyte, wherein said method comprises:

(a) generating, using a signal averaging technique, an electrical recording result from an organ within said human,

(b) comparing said result to a signal template to obtain an indication of the level of said analyte in said human, and

(c) comparing the level of said analyte in said human to said previously determined level of said analyte to determine a change, wherein said change is a change that is not detectable based on visual inspection of an electrical recording of said organ.

14. The method of claim 13 , wherein said organ is a heart.

15. The method of claim 13 , wherein said electrical recording result is an ECG tracing.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Mar 1, 2021
From: CRG SERVICING LLC
To: PREVENTICE TECHNOLOGIES, INC., F/K/A BOOST INFORMATION SYSTEMS, INC.
Reel/Frame 055448/0894 →
SECURITY INTEREST Recorded Feb 5, 2019
From: PREVENTICE TECHNOLOGIES, INC., F/K/A BOOST INFORMATION SYSTEMS, INC.
To: CRG SERVICING LLC
Reel/Frame 048244/0262 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 19, 2013
From: FRIEDMAN, PAUL A.; BENNET, KEVIN E.; BRUCE, CHARLES J.; SOMERS, VIREND K.
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 030640/0182 →
Continuity (2)
Provisional Application 61364317 · Jul 14, 2010
Related Publication 20130184599A1 · Jul 18, 2013