Granted Patent
B2
US 8,735,390 · App. 13/821,585 · Granted May 27, 2014
Polymorphs and salts
Inventors:
Julie Nicole Hamblin (Stevenage, GB); Paul Spencer Jones (Stevenage, GB); Suzanne Elaine Keeling (Stevenage, GB); Joelle Le (Stevenage, GB); Charlotte Jane Mitchell (Stevenage, GB); Nigel James Parr (Stevenage, GB); Robert David Willacy (Stevenage, GB)
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Abstract
The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity.
Claims (3)
1. A polymorph (Form III) of N-[5-[4-(5-{[(2R,6S)-2,6-dimethyl -4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-(methyloxy) 3-pyridinyl]methanesulfonamide characterised in that it provides an XRPD pattern comprising peaks (°2θ) at about 6.7, about 8.2, about 9.7 and/or about 12.6.
2. A polymorph according to claim 1 characterised in that it provides an XRPD pattern comprising peaks substantially as set out in Table 2.
3. A polymorph according to claim 1 characterised in that it provides an XRPD pattern substantially in accordance with FIG. 2 .
Assignments (3)
CHANGE OF ADDRESS
Recorded Apr 16, 2025
From: GLAXO GROUP LIMITED
To: GLAXO GROUP LIMITED
Reel/Frame 071044/0904 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 31, 2014
From: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
To: GLAXO GROUP LIMITED
Reel/Frame 033452/0594 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 24, 2013
From: HAMBLIN, JULIE NICOLE; JONES, PAUL SPENCER; KEELING, SUZANNE ELAINE; LE, JOELLE; MITCHELL, CHARLOTTE JANE; PARR, NIGEL JAMES; WILLACY, ROBERT DAVID
To: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
Reel/Frame 031466/0178 →
Continuity (2)
Provisional Application
61380748
· Sep 8, 2010