Syringe with two-stage sealing pressure
A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges −25° C. to 40° C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.
1. A method for storing and dispensing a product having a high content of water, the method comprising:
providing a syringe barrel having a cylindrical wall, the cylindrical wall having a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter;
providing a plunger having a sealing member;
inserting the plunger into the barrel;
adding product to the first portion and the second portion of the syringe barrel such that the plunger is positioned within the first portion of the barrel;
engaging the first portion of the barrel with the sealing member to give rise to a first contact pressure when the first portion and the second portion include the product;
applying a first force to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product;
engaging the second portion of the barrel with a portion of the plunger to give rise to a second contact pressure that is lower than the first contact pressure; and
applying a second force lower than the first force to overcome the second contact pressure to move the plunger in the second portion to continue dispensing product.
2. The method of claim 1 , wherein giving rise to the first contact pressure includes creating a gas-tight seal between the plunger and barrel through a temperature range of −25° C. to 40° C.
3. The method of claim 1 , wherein providing a plunger having a sealing member includes providing a plunger with at least one o-ring as the sealing member;
wherein engaging the second portion of the barrel with a portion of the plunger includes engaging the second portion of the barrel with the at least one o-ring; and
wherein the o-ring gas-tightly seals against both of the first and second portions.
4. The method of claim 1 , wherein engaging the first portion of the barrel with the sealing member includes gas-tightly sealing the plunger with respect to the first portion of the barrel with the sealing member; and
wherein engaging the second portion of the barrel with a portion of the plunger does not include gas-tightly sealing the plunger with respect to the second portion of the barrel with the sealing member.
5. The method of claim 1 , wherein providing a plunger having a sealing member includes providing a plunger head having a sealing member and at least one rim; and
wherein engaging the second portion of the barrel with a portion of the plunger includes engaging the second portion of the barrel the at least one rim and not with the sealing member.
6. The method of claim 1 , further comprising inserting a reduced diameter member into the barrel to create the first portion of the barrel.
7. The method of claim 1 , wherein providing a plunger having a sealing member includes providing the plunger having a flexible member as the sealing member.
8. The method of claim 1 , further comprising defining a step between the first and second portions of the barrel; and engaging the step with the sealing member to resist movement of the plunger in a rearward direction with respect to the barrel.