Hydrogen peroxide-based skin disinfectant
View Patent ↗An aqueous skin disinfecting solution has a pH of from about 2 to about 6, and consists of at least (a) hydrogen peroxide in a concentration of from about 0.01 to about 4% w/w; (b) at least one surfactant chosen from alkyl betaines, alkyl amidopropyl betaines, alkyl amidopropyl betaine amides, alkylsulfobetaines, alkyl amphocarboxylates and amine oxides in a concentration of from about 0.01 to about 15% w/w; (c) at least one hydrogen peroxide stabilizer in a concentration of from about 0.01 to about 4% w/w; (d) at least one member chosen from cyclic carboxylic acids and salts thereof in a concentration of from about 0.01 to about 4% w/w; (e) at least one skin conditioning agent in a concentration of from about 0.01 to about 10% w/w; and (f) an effective amount of at least one solvent. The invention can be provided in concentrated or dried powdered form.
1. An aqueous skin disinfecting solution for use in disinfecting skin, having a pH of from about 2 to about 6, and consisting of:
(a) hydrogen peroxide in a concentration of from about 0.01 to about 4% w/w;
(b) at least one surfactant selected from the group consisting of alkyl betaines, alkyl amidopropyl betaines, alkyl amidopropyl betaine amides, alkylsulfobetaines, alkyl amphocarboxylates and amine oxides in a concentration of from about 0.01 to about 15% w/w;
(c) at least one hydrogen peroxide stabilizer selected from the group consisting of phosphoric acid, phosphonic acids having 1 to 5 phosphonic acid groups, ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA), N-(hydroxyethyl)-ethylenediaminetriacetic acid (HEDTA), nitrilotriacetic acid (NTA), 2-hydroxyethyliminodiacetic acid (HEIDA), benzoic acid, aminobenzoic acid, citric acid, iminodisuccinic acid, polyaspartic acid, and salts thereof in a concentration of from about 0.01 to about 4% w/w;
(d) at least one member chosen from cyclic carboxylic acid and salts thereof in a concentration of from about 0.01 to about 4% w/w;
(e) at least one skin conditioning agent selected from the group consisting of glycerin, glycerides, sorbitol, castor oil, allantoin, cationic polymers, lanolin, and cetyl alcohol in a concentration of from about 0.01 to about 10% w/w;
(f) optionally, an effective amount of propylene glycol;
(g) optionally, at least one buffer in a concentration of from about 0.01 to about 5% w/w;
(h) optionally, at least one thickening agent compatible with hydrogen peroxide in a concentration of from about 0.01 to about 5% w/w;
(i) optionally, at least one C1 to C8 alcohol in a concentration of from about 0.01 to about 10% w/w;
(j) optionally, at least one member selected from the group consisting of dyes and fragrances in a concentration of from about 0.001 to about 0.5% w/w; and
(k) water q.s. to 100% w/w.
2. The solution of claim 1 , wherein said at least one cyclic carboxylic acid is selected from the group consisting of benzoic acid, salicylic acid, and 2-furan carboxylic acid.
3. The solution of claim 2 , wherein said at least one of salicylic acid, benzoic acid, and 2-furan carboxylic acid is present in a concentration of from about 0.05 to about 1% w/w.
4. The solution of claim 3 , wherein said at least one cyclic carboxylic acid is selected from the group consisting of salicylic acid and benzoic acid.
5. The solution of claim 1 , wherein glycerin is present in the solution.
6. The solution of claim 1 , wherein the pH of the solution is from about 2 to about 4.
7. The solution of claim 1 , wherein said at least one buffer is selected from the group consisting of citric acid, lactic acid, glycolic acid, phosphoric acid, malic acid, succinic acid and tartaric acid and is present in the solution.
8. The solution of claim 1 , wherein the solution has a hydrogen peroxide concentration of from about 0.25 to about 3% w/w.
9. The solution of claim 1 , wherein said at least one C1 to C8 alcohol is selected from the group consisting of benzyl alcohol, ethanol, n-butanol, isopropanol, and glycols and is present in the solution.
10. The solution of claim 1 , wherein at least one amine oxide is present in the solution in a concentration of from about 1 to about 5% w/w.
11. The solution of claim 1 , wherein the pH is from about 2 to about 2.5.