Myocardial perfusion imaging methods and compositions
View Patent ↗A myocardial imaging method that is accomplished by administering one or more adenosine A 2A adenosine receptor agonist to a human undergoing myocardial imaging as well as pharmaceutical compositions comprising at least one A 2a receptor agonist, at least one liquid carrier, and at least one co-solvent.
1. A method for myocardial perfusion imaging comprising administering to a human subject in need thereof a compound which has the formula:
with saline and followed by a radionuclide, wherein the myocardium is examined for areas of insufficient blood flow following the administration of the radionuclide.
2. The method of claim 1 , wherein the method comprises administering the compound by intravenous (iv) bolus.
3. A method for myocardial perfusion imaging comprising administering a single bolus intravenous injection of a pharmaceutical composition comprising a compound which has the formula:
to a human subject in need thereof, wherein the compound is administered in an amount of 10 μg to about 1000 μg, and the amount is independent of the human subject's weight.