Magnetic confinement for microbeam radiation damage area
Various embodiments relate to a method of performing microbeam radiation therapy on a subject, including: producing a high-energy radiation beam in a first direction; producing planar microbeams using the high-energy radiation beam in the first direction, wherein the microbeams have a width, wherein the planar microbeams produce scattered electrons; and applying a magnetic field in a direction lying in a plane substantially parallel to the planar microbeams, wherein the strength of the magnetic field corresponds to the width of the microbeam.
1. A method of performing microbeam radiation therapy on a subject, comprising:
producing a high-energy radiation beam in a first direction;
producing planar microbeams using the high-energy radiation beam in the first direction, wherein the microbeams have a width, wherein the planar microbeams produce scattered electrons; and
applying a magnetic field in a direction lying in a plane substantially parallel to the planar microbeams, wherein the strength of the magnetic field corresponds to the width of the microbeam,
wherein the magnetic field is produced in non-targeted normal tissues of the subject.
2. The method of claim 1 , wherein the magnetic field causes the scattered electrons in the magnetic field to move in a circular path with a radius in a plane substantially perpendicular to the direction of the applied magnetic field.
3. The method of claim 2 , wherein radius is less than 0.2 of the width of the microbeams.
4. The method of claim 2 , wherein radius is less than 0.1 of the width of the microbeams.
5. The method of claim 2 , wherein radius is less than 0.05 of the width of the microbeams.
6. The method of claim 2 , wherein radius is less than 0.01 of the width of the microbeams.
7. The method of claim 1 , wherein the magnetic field is produced by a permanent magnet.
8. The method of claim 1 , wherein the magnetic field is produced by an electromagnet.
9. The method of claim 8 , wherein the magnetic field is produced by a super conducting magnet.
10. The method of claim 1 , further comprising:
producing a high-energy radiation beam in a second direction;
producing second planar microbeams using the high-energy radiation beam in the second direction, wherein the microbeams have a second width, wherein the second planar microbeams produce scattered electrons; and
applying a second magnetic field in a second direction lying in a plane substantially parallel to the second planar microbeams, wherein the strength of the magnetic field corresponds to the second width of the second microbeams.
11. A microbeam radiation therapy system, comprising:
a high-energy radiation beam;
a collimator with slits, wherein the collimator only passes the high-energy radiation beam through the slits;
a beam filtering and limiting system; and
a magnet producing a magnetic field in a direction substantially parallel to slits of the collimator, wherein the magnetic field intersects the high-energy radiation beam that passes through the slits, and wherein the magnetic field is produced in non-targeted normal tissues of a subject.
12. The system of claim 11 , wherein the magnet produces a magnetic field that causes scattered electrons in the magnetic field to move in a circular path with a radius in a plane substantially perpendicular to the direction of the applied magnetic field.
13. The system of claim 12 , wherein radius is less than 0.2 of the width of the microbeams.
14. The system of claim 12 , wherein radius is less than 0.1 of the width of the microbeams.
15. The system of claim 12 , wherein radius is less than 0.05 of the width of the microbeams.
16. The system of claim 12 , wherein radius is less than 0.01 of the width of the microbeams.
17. The system of claim 11 , wherein the magnet is a permanent magnet.
18. The system of claim 11 , wherein the magnet is an electromagnet.
19. The system of claim 11 , wherein the magnet is a super conducting magnet.
20. The system of claim 11 , wherein the system is configured to provide radiation treatment in two different directions.