Encapsulated solid hydrophilic particles
View Patent ↗A process of forming microcapsules is described. The microcapsule population is formed by providing an anionic or cationic, solid hydrophilic core material; providing an oil continuous phase, the oil continuous phase comprising one or more esters with chain length up to about 18 carbons. Emulsification is achieved by subjecting the mixture to high shear agitation and heating the mixture for a time sufficient to enable acid or amine acrylate or methacrylate and multifunctional acrylate or methacrylate to form a prepolymer which migrates to the anionic or cationic solid hydrophilic material, thereby forming prepolymers adhered to the hydrophilic core materials. Temperature is held or heating continued for a time sufficient to enable the prepolymer to flow onto and coalesce into a continuous film surface coating on the hydrophilic core material. Heating is carried out or light exposure or both for a time and temperature sufficient to cross link the prepolymers.
1. A process of forming a population of microcapsules comprising a solid hydrophilic core material and a wall material at least partially surrounding the core material, the microcapsule population being formed by:
providing particles of a solid hydrophilic core material;
providing an oil continuous phase which is low boiling, the oil continuous phase comprising esters or one or more hydrocarbons with chain length up to about 18 carbons;
forming a mixture by:
adding an oil soluble or dispersible amine acrylate or methacrylate;
adding a multifunctional acrylate or methacrylate monomer or oligomer;
adding an acid and an initiator;
optionally adding a surfactant;
dispersing the mixture in the continuous phase by subjecting the mixture to agitation; heating the mixture for a time sufficient to enable the amine acrylate or methacrylate and the multifunctional acrylate or methacrylate to form a cationic prepolymer;
dispersing the solid hydrophilic material in the oil continuous phase whereby the cationic prepolymer migrates to the solid hydrophilic material, thereby forming prepolymer adhered to the hydrophilic core materials;
holding the temperature for a time sufficient to enable the cationic prepolymer to flow onto and coalesce into a continuous film surface coating on the hydrophilic core material;
heating for a time and temperature sufficient to cross link the prepolymer continuous film surface coating on the particles.
2. The process of forming a population of microcapsules according to claim 1 wherein the acid and the amine acrylate or methacrylate have a percent by weight as compared to weight of the we material of from 0.1 to 25 percent.
3. The process of forming a population of microcapsules according to claim 1 wherein the weight ratio of the amine to the multifunctional acrylate or methacrylate is from 0.1:99.9 to 10:90.
4. The process of forming a population of microcapsules according to claim 1 wherein the acid and the amine acrylate or methacrylate have a molar proportion of from 1.5/1 to about 1/1.5.
5. The process of forming a population of microcapsules according to claim 1 wherein the solid hydrophilic core material is selected from the group consisting of anionic, cationic, or neutral but polar material.
6. The process of forming a population of microcapsules according to claim 1 wherein the amine acrylate or methacrylate is selected from a monofunctional amine acrylate or a monofunctional amine methacrylate with a nitrogen content of 5% by weight or greater.
7. The process of forming a population of microcapsules according to claim 1 wherein the amine acrylate is selected from the group consisting of alkyl amino acrylate and alkylaminomethacrylate having a nitrogen content of 5% by weight or greater.
8. The process of forming a population of microcapsules according to claim 1 wherein the acid is a carboxylic acid acrylate or carboxylic acid methacrylate having a —COOH content of 20% or greater by weight.
9. The process according to claim 1 wherein the wail material is selected to be a water permeable, partially water permeable, water soluble, partially water soluble, water fracturable, water disintegratable, semi-porous or an osmotic material.
10. The process according to claim 1 wherein the oil continuous phase comprises in addition sucrose octyl stearate, a polysaccharide, polyethylene glycol, esters of polyethylene glycol, esterified polyol, saccharide ester, or wax.
11. The process according to claim 1 wherein a water soluble polymer is added in addition to the multifunctional acrylate.
12. The process of forming a population of microcapsules according to claim 1 wherein the oil continuous phase is selected from the group consisting of isoamyl benzoate, capric triglyceride, caprylic triglyceride and blends thereof.
13. The process of forming a population of microcapsuies according to claim 1 wherein forming or crosslinking the prepolymers is accomplished by heating the mixture or exposing the mixture to actinic radiation or both.