IP Library Granted Patent US 9,211,213
Granted Patent B2
US 9,211,213 · App. 13/865,770 · Granted Dec 15, 2015

Ocular implants and methods for delivering ocular implants into the eye

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Quick Facts
Patent No.
US 9,211,213
App. No.
13/865,770
Granted
Dec 15, 2015
Kind
B2
Abstract

An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.

Claims (35)

1. An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye, the eye having an iris defining a pupil, the implant comprising:

a longitudinally extending curved body including a proximal portion and a distal portion, the distal portion of the curved body having a central longitudinal axis defined by a radius of curvature and a lateral cross section having a first lateral extent and a second lateral extent, an aspect ratio of the first lateral extent to the second lateral extent being greater than or equal to about two;

the distal portion of the curved body defining a longitudinal channel including a channel opening, the channel opening included in defining the first lateral extent; and

the curved body being adapted and configured such that the distal portion of the curved body resides in Schlemm's canal and the proximal portion extends into the anterior space of the eye while the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is implanted.

2. The ocular implant of claim 1 wherein the channel opens away from the pupil when the channel opening is adjacent an outer major side of Schlemm's canal, the outer major side being further from the pupil than an inner major side of Schlemm's canal.

3. The ocular implant of claim 1 wherein:

the channel has a width and a depth; and

an aspect ratio of the width to the depth is such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal.

4. The ocular implant of claim 3 wherein the aspect ratio of the width to the depth is about two.

5. The ocular implant of claim 1 , wherein the body defines additional openings fluidly communicating with the channel and the body of the implant is more than 50% open due to the openings defined by the body.

6. The ocular implant of claim 1 , wherein the body is curved about a lateral central axis so that a longitudinal axis of the body defines a plane.

7. The ocular implant of claim 6 , wherein the body has a lateral radius of curvature extending between the lateral central axis and an outer extent of the body.

8. The ocular implant of claim 7 , wherein the lateral radius of curvature is substantially constant.

9. The ocular implant of claim 7 , wherein the lateral radius of curvature varies along a length of the body.

10. An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye, the eye having an iris defining a pupil, the implant comprising:

a longitudinally extending curved body including a proximal portion and a distal portion, the distal portion of the curved body having a central longitudinal axis defined by a radius of curvature and a lateral cross section having a first lateral extent and a second lateral extent, an aspect ratio of the first lateral extent to the second lateral extent being greater than or equal to about two, the lateral cross section further having a shape defining an inner concave surface and an outer convex surface, each extending over a substantial portion of the length of the distal section;

the inner concave surface defining a longitudinal channel extending over a substantial portion of the length of the distal portion and including a channel opening, the channel opening being across from the inner concave surface; and

the body being adapted and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in the eye.

11. The ocular implant of claim 10 wherein the channel opens away from the pupil when the channel opening is adjacent an outer major side of Schlemm's canal, the outer major side being further from the pupil than an inner major side of Schlemm's canal.

12. The ocular implant of claim 10 wherein:

the channel has a width and a depth; and

an aspect ratio of the width to the depth is such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal.

13. The ocular implant of claim 12 wherein the aspect ratio of the width to the depth is about two.

14. The ocular implant of claim 10 , wherein the body defines additional openings fluidly communicating with the channel and the body of the implant is more than 50% open due to the openings defined by the body.

15. The ocular implant of claim 10 , wherein the body is curved about a lateral central axis so that a longitudinal axis of the body defines a plane.

16. The ocular implant of claim 15 , wherein the body has a lateral radius of curvature extending between the lateral central axis and an outer extent of the body.

17. The ocular implant of claim 16 , wherein the lateral radius of curvature is substantially constant.

18. The ocular implant of claim 16 , wherein the lateral radius of curvature varies along a length of the body.

19. An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye, the eye having an iris defining a pupil, the implant comprising:

a longitudinally extending body having a lateral cross section defining a first lateral extent and a second lateral extent, an aspect ratio of the first lateral extent to the second lateral extent being greater than or equal to two;

the body being curved about a longitudinal central axis so that the lateral cross section further defines an inner concave surface and an outer convex surface;

a distal portion of the body defining a longitudinal channel including a channel opening, the channel opening being across from the inner concave surface; and

the body being adapted and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal.

20. The ocular implant of claim 19 wherein the channel opens away from the pupil when the channel opening is adjacent an outer major side of Schlemm's canal, the outer major side being further from the pupil than an inner major side of Schlemm's canal.

21. The ocular implant of claim 19 , wherein the body defines additional openings fluidly communicating with the channel and the body of the implant is more than 50% open due to the openings defined by the body.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2022
From: IVANTIS, INC.
To: ALCON INC.
Reel/Frame 061161/0697 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 24, 2013
From: WARDLE, JOHN; SCHIEBER, ANDREW T.; GALT, KENNETH M.
To: IVANTIS, INC.
Reel/Frame 031272/0290 →