Delivery system for ocular implant
View Patent ↗A delivery system is disclosed which can be used to deliver an ocular implant into a target location within the eye via an ab interno procedure. In some embodiments, the implant can provide fluid communication between the anterior chamber and the suprachoroidal or supraciliary space while in an implanted state. The delivery system can include a proximal handle component and a distal delivery component. In addition, the proximal handle component can include an actuator to control the release of the implant from the delivery component into the target location in the eye.
1. A delivery device for delivering an ocular implant into an eye, the delivery device comprising:
a proximal handle portion;
a distal delivery portion coupled to a distal end of the handle portion and configured to releasably hold an ocular implant, the delivery portion comprising a sheath positioned axially over a guidewire that inserts through the ocular implant when the ocular implant is mounted on the guidewire such that only the guidewire is inserted into the ocular implant; and
an actuator coupled to a mechanism that releases the ocular implant from the delivery portion upon actuation of the actuator, wherein the guidewire is coupled to a part of the mechanism which includes a spring, wherein actuation of the actuator causes the spring to retract the guidewire; and
a dampener coupled to the handle portion, the dampener adapted to dampen retraction of the guidewire upon actuation of the actuator
wherein the guidewire includes at least one non-spiraled curved section that at least partially retains the implant on the guidewire during delivery into the eye, wherein the curved section forms a radius of curvature that is tighter than a radius of curvature of the entire guidewire.
2. The delivery device of claim 1 , wherein a distal end of the guidewire extends distally from a distal end of the sheath when the spring is in a first formation.
3. The delivery device of claim 2 , wherein the distal end of the guidewire proximally retracts from the distal end of the sheath when the spring is in a second formation.
4. The delivery device of claim 3 , wherein actuation of the actuator causes the spring to transition between the first formation and the second formation.
5. The delivery device of claim 1 , wherein a distal end of the sheath at least one of receives or abuts a proximal end of the ocular implant and prevents the ocular implant from sliding in a proximal direction as the guidewire proximally retracts.
6. The delivery device of claim 1 , wherein the curved section includes a radius of curvature in the range of 0.425 inches to 0.525 inches with a central angle in the range of 20 degrees to 40 degrees.
7. The delivery device of claim 1 , wherein the guidewire includes at least one inner lumen.
8. The delivery device of claim 7 , wherein the guidewire includes at least one opening along a length of the guidewire which provides fluid communication between the inner lumen of the guidewire and an area surrounding the guidewire.
9. The delivery device of claim 8 , wherein the implant includes at least one hole along a length of the ocular implant which provides fluid communication between the inner lumen of the implant and an area surrounding the ocular implant.
10. The delivery device of claim 1 , wherein the delivery device includes at least one fluid delivery feature which delivers fluid from a fluid source to at least one of the ocular implant or the eye.
11. The delivery device of claim 10 , wherein the fluid from the fluid source includes one or more of a viscoelastic, a drug and a stem cell.