IP Library Granted Patent US 9,131,867
Granted Patent B2
US 9,131,867 · App. 13/867,804 · Granted Sep 15, 2015

Atrial fibrillation detection

Inventors: Raymond C. Kurzweil (Newton, MA); Lucy Gibson (Belmont, MA); Paul Albrecht (Bedford, MA); Paul Grimshaw (Acton, MA)
Assignee: Medicomp, Inc.
A61B5/046
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Quick Facts
Patent No.
US 9,131,867
App. No.
13/867,804
Granted
Sep 15, 2015
Kind
B2
Abstract

A method of detecting atrial fibrillation (AFib) includes receiving electrical signals representative of a beating heart and measuring atrial activity over a time window of three or more beats. The method may also include measuring beat interval variation over the time window and combining the measures of atrial activity and beat interval variation to produce an indication of an atrial fibrillation condition in the electrical signal. The method may further include producing the indication with a processing system. Measuring atrial activity may include measuring P waves, and measuring P waves may include analyzing a standard deviation of a PR interval.

Claims (48)

1. A method of detecting atrial fibrillation (AFib), the method comprising:

receiving electrical signals representative of a beating heart;

measuring atrial activity over a time window of three or more beats;

measuring beat interval variation over the time window;

combining the measures of atrial activity and beat interval variation to produce an indication of an atrial fibrillation condition in the electrical signal; and

producing the indication with a processing system;

wherein measuring atrial activity further comprises measuring conduction of at least one P

wave by analyzing a standard deviation of a PR interval for the at least one P wave.

2. The method of claim 1 , wherein the at least one P wave is classified as conducting when the standard deviation of the PR interval for the at least one P wave is low.

3. The method of claim 2 , wherein the at least one P wave comprises a plurality of P waves, and wherein the classification of the PR interval as an irregular rhythm other than AFib depends on a count of the plurality of P waves detected in the PR interval classified as conducting.

4. The method of claim 3 , wherein a hysteresis filter is utilized to increase reliability of the count of the conducting P waves.

5. The method of claim 2 wherein the electrical signals are provided from plural electrical channels and wherein the method further comprises:

determining whether one or more P waves are detected during a TQ interval on a channel from the plural channels with a largest expected P-wave;

combining a number and times of detected P waves from that channel when plural P-waves are detected; otherwise,

combining a number and times of detected P waves from an alternate one of the plural channels.

6. The method of claim 2 wherein measuring atrial activity further comprises computing a measure of a fraction of beat intervals that have one detected P wave.

7. The method of claim 2 wherein measuring atrial activity further comprises determining if more than one P wave is present in a beat interval.

8. The method of claim 1 wherein measuring atrial activity further comprises using information from more than one signal channel representative of a beating heart to detect and classify the at least one P wave.

9. The method of claim 8 wherein measuring atrial activity further comprises:

measuring the atrial activity for a plurality of channels;

determining a quality indicator for the measured channels; and

selecting one of the measures from the channels based at least in part on the determined quality indicators for the measured channels.

10. The method of claim 1 wherein measuring atrial activity, measures the atrial activity over the time window and further comprises:

producing two or more atrial activity measures in the time window; and

combining the atrial activity measures into a representative atrial activity measure for the time window.

11. A computer program product residing on a computer readable medium for detecting atrial fibrillation in an electrical signal, the computer program product comprising instructions for causing a computer to:

receive the electrical signal representative of a beating heart;

measure atrial activity over a time window of three or more beats;

measure beat interval variation over the time window;

combine the measures of atrial activity and beat interval variation to produce an indication of an atrial fibrillation condition in the electrical signal; and

produce the indication;

wherein instructions for causing a computer to measure atrial activity comprise instructions for causing a computer to measure conduction of at least one P

wave by analyzing a standard deviation of a PR interval for the at least one P wave.

12. The computer program product of claim 11 , wherein instructions to classify the at least one P wave, classify the at least one P wave as conducting when the standard deviation of the PR interval for the at least one P wave is low.

13. The computer program product of claim 12 , wherein the at least one P wave comprises a plurality of P waves, and wherein instructions to classify the PR interval as an irregular rhythm other than AFib depends on a count of the plurality of P waves detected in the PR interval classified as conducting.

14. The computer program product of claim 13 , wherein instructions to classify the PR interval utilize a hysteresis filter to increase reliability of the count of the conducting P waves.

15. The computer program product of claim 12 , wherein the instructions to classify the at least one P wave further provisionally classify each of the at least one P wave as conducted or non-conducted.

16. The computer program product of claim 12 wherein the instructions to detect P-waves further comprise instructions to:

compute a measure of a fraction of beat intervals that have one detected P wave.

17. The computer program product of claim 12 wherein instructions for measuring atrial activity, determine if more than one P wave is present in a beat interval.

18. The computer program product of claim 12 wherein instructions for measuring atrial activity further comprise using information from more than one signal channel representative of a beating heart to detect and classify the P waves.

19. The computer program product of claim 18 wherein instructions for measuring atrial activity further comprises:

measuring the atrial activity for a plurality of channels;

determining a quality indicator for the measured channels; and

selecting one of the measures from the channels based at least in part on the determined quality indicators for the measured channels.

20. The computer program product of claim 11 wherein instructions for measuring atrial activity, measures the atrial activity over the time window and further comprises:

producing two or more atrial activity measures in the time window; and

combining the atrial activity measures into a representative atrial activity measure for the time window.

Assignments (5)
SECURITY INTEREST Recorded Jun 30, 2026
From: MEDICOMP, INC.
To: FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 075142/0291 →
RELEASE OF SECURITY INTEREST Recorded Oct 3, 2025
From: TRUIST BANK
To: MEDICOMP, INC.
Reel/Frame 072457/0824 →
SECURITY INTEREST Recorded Sep 30, 2025
From: MEDICOMP, INC.; WATERMARK MEDICAL, INC.
To: FIFTH THIRD BANK, NATIONAL ASSOCIATION
Reel/Frame 072430/0464 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Jan 4, 2023
From: MEDICOMP, INC.
To: TRUIST BANK
Reel/Frame 062278/0308 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2013
From: KURZWEIL, RAYMOND C.; GIBSON, LUCY; ALBRECHT, PAUL; GRIMSHAW, PAUL
To: MEDICOMP, INC.
Reel/Frame 030890/0550 →
Continuity (3)
Continuation 12564271 · Sep 22, 2009
Continuation 11074320 · Mar 7, 2005
Related Publication 20130303926A1 · Nov 14, 2013