Copolymers for intraocular lens systems

1. An intraocular lens comprising a copolymeric composite material comprising:

a silicone component, and

an acrylic component; wherein the acrylic component comprises:

an acrylate recurring unit; and

an optionally substituted vinylaryl recurring unit;

wherein a portion of said acrylate recurring units and optionally substituted vinylaryl recurring units comprise a vinyldialkylsiloxy pendant group; and

wherein said copolymeric composite material comprises a plurality of silicon-carbon covalent bonds between a silicon atom of the silicone component and a carbon atom of a vinyldialkylsiloxy pendant group, and

further wherein said silicon-carbon covalent bonds are created via a hydrosilylation reaction between said vinyldialkylsiloxy pendant group on at least one of the acrylate recurring units and an Si—H group of the silicone component.

2. The intraocular lens of claim 1 , wherein the acrylic component comprises the following recurring units:

wherein R 1 and R 2 are independently C 1-12 alkyl or optionally substituted phenyl;

X is C 1-4 alkyl;

Y 1 , Y 2 , and Y 3 are independently H or C 1-4 alkyl;

Ph 1 and Ph 2 are independently optionally substituted phenyl;

each R 3 and each R 4 is independently C 1-4 alkyl or

each R 5 and each R 6 is independently, C 1-4 alkyl;

R 7 is a covalent bond or C 1-6 alkyl; and

R 8 is C 1-6 alkyl.

3. The intraocular lens of claim 2 , further comprising:

an anterior viewing element;

a posterior viewing element; and

a biasing structure connecting the anterior viewing element to the posterior viewing element;

wherein the biasing structure provides a variable spacing between the anterior viewing element and the posterior viewing element;

wherein at least a portion of at least one of: the anterior viewing element and the posterior viewing element comprises at least a portion of the acrylic component;

at least a portion of at least one of the anterior viewing element, the posterior viewing element, and the biasing structure comprises at least a portion of the silicone component; and

at least a portion of at least one of the anterior viewing element, the posterior viewing element, and the biasing structure comprises at least a portion of the plurality of silicon-carbon covalent bonds.

4. The intraocular lens of claim 3 , wherein the acrylic component comprises at least a portion of the anterior viewing element or at least a portion of the posterior viewing element, and the silicone component comprises at least a portion of the biasing structure.

5. The intraocular lens of claim 3 , wherein the acrylic component comprises at least a portion of the anterior viewing element and at least a portion of the posterior viewing element, and the silicone component comprises at least a portion of the biasing structure.

6. The intraocular lens of claim 3 , wherein R 1 of the acrylic component is n-butyl.

7. The intraocular lens of claim 3 , wherein R 2 of the acrylic component is ethyl and X of the acrylate component is methyl.

8. The intraocular lens of claim 3 , wherein each R 3 of the acrylic component is vinyldimethylsiloxy or methyl.

9. The intraocular lens of claim 3 , wherein each R 4 of the acrylic component is vinyldimethylsiloxy or methyl.

10. The intraocular lens of claim 3 , wherein each R 5 of the acrylic component is methyl.

11. The intraocular lens of claim 3 , wherein each R 6 of the acrylic component is methyl.

12. The intraocular lens of claim 3 , wherein R 7 of the acrylic component is —CH 2 —, —CH 2 CH 2 —, or —CH 2 CH 2 CH 2 —.

13. The intraocular lens of claim 3 , wherein R 8 of the acrylic component is —(CH 2 ) 3 — or —(CH 2 ) 4 —.

14. The intraocular lens of claim 3 , wherein X of the acrylic component is methyl.

15. The intraocular lens of claim 3 , wherein Y 1 of the acrylic component is hydrogen or methyl.

16. The intraocular lens of claim 3 , wherein Y 2 of the acrylic component is hydrogen or methyl.

17. The intraocular lens of claim 3 , wherein Y 3 of the acrylic component is hydrogen or methyl.

18. The intraocular lens of claim 3 , wherein Ph 1 of the acrylic component is unsubstituted phenyl.

19. The intraocular lens of claim 3 , wherein Ph 2 of the acrylic component is unsubstituted phenyl.

20. The intraocular lens of claim 3 , wherein the acrylic component is a copolymer prepared by a process comprising:

reacting:

monomer 1a, monomer 2, and monomer 3a; and

monomer 4 or monomer 5a;

wherein monomer 1a is represented by a formula:

monomer 2 is represented by a formula:

monomer 3a is represented by a formula:

monomer 4 is represented by a formula:

and

monomer 5a represented by a formula:

and

R 1 and R 2 are independently C 1-12 alkyl or optionally substituted phenyl;

X is C 1-4 alkyl;

Y 1 , Y 2 , and Y 3 are independently H or C 1-4 alkyl;

Ph 1 and Ph 2 are independently optionally substituted phenyl;

each R 3 and each R 4 is independently C 1-4 alkyl or

each R 5 and each R 6 is independently C 1-4 alkyl;

R 7 is a covalent bond or C 1-6 alkyl; and

R 8 is C 1-6 alkyl.

21. The intraocular lens of claim 20 , wherein monomer 2 comprises ethyl methacrylate.

22. The intraocular lens of claim 20 , wherein monomer 3a comprises methylstyrene.

23. The intraocular lens of claim 20 , wherein monomer 5a comprises methacryloxypropyltris(vinyldimethylsiloxy)silane.

24. The intraocular lens of claim 20 , further comprising reacting ethylene glycol dimethacrylate at any point in the process.

25. The intraocular lens of claim 20 , further comprising reacting 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate at any point in the process.

26. The intraocular lens of claim 20 , wherein the process comprises a radical process initiated by 2,2′-azobisisobutyronitrile.

27. The intraocular lens of claim 20 , wherein monomer 1a represents about 40% to about 55% of the total weight of all monomers present in the process.

28. The intraocular lens of claim 20 , wherein monomer 2 represents about 15% to about 25% of the total weight of all monomers present in the process.

29. The intraocular lens of claim 20 , wherein monomer 3a represents about 15% to about 20% of the total weight of all monomers present in the process.

30. The intraocular lens of claim 20 , wherein monomer 4 represents about 2% to about 20% of the total weight of all monomers present in the process.

31. The intraocular lens of claim 20 , wherein the plurality of silicon-carbon covalent bonds comprise a covalent bond between an R 9 and a Z 1 or an R 10 and a Z 2 in a plurality of recurring units represented by a formula:

wherein Y is H or C 1-4 alkyl;

Ph 2 is optionally substituted phenyl;

each R 3 and each R 4 is independently C 1-4 alkyl or

and

each R 5 and each R 6 is independently C 1-4 alkyl;

R 7 is a covalent bond or C 1-6 alkyl; and

R 8 is C 1-6 alkyl;

R 9 and R 10 are C 2 H 4 ; and

Z 1 and Z 2 are each a Si atom from an H—Si moiety of the silicone component wherein the H atom has been replaced with R 9 or R 10 .

32. The intraocular lens of claim 20 , wherein monomer 1a comprises n-butyl acrylate.