Liquid formulations of urease inhibitors for fertilizers
An improved solvent system for the formulation and application of N-alkyl thiophosphoric triamide urease inhibitors. These formulations provide safety and performance benefits relative to existing alternatives and enable storage, transport and subsequent coating or blending with urea based or organic based fertilizers. These formulations are comprised primarily of environmentally friendly aprotic and protic solvents (particularly dimethyl sulfoxide and alcohols/polyols) to stabilize the urease inhibitor.
1. A formulation comprising N-(n-butyl) thiophosphoric triamide and dimethyl sulfoxide, or R 1 S(O)R 2 wherein R 1 is methyl, ethyl, n-propyl, phenyl or benzyl and R 2 is ethyl, n-propyl, phenyl or benzyl; and one or more members selected from the group consisting of ethylene or propylene carbonate; or mixtures thereof,
an alcohol or a polyol selected from the group consisting of alkylene and poly(alkylene) glycols, glycerin, and ethyl, propyl or butyl lactate; wherein the formulation is prepared by dissolving the N-(n-butyl) thiophosphoric triamide into the dimethyl sulfoxide, or R 1 S(O)R 2 , and wherein the formulation further has the alcohol or the polyol selected from the group consisting of alkylene and poly(alkylene) glycols, glycerin, or the ethylene or propylene carbonate, or the ethyl, propyl or butyl lactate added to the formulation.
2. The formulation of claim 1 , wherein the formulation comprises dimethyl sulfoxide.
3. The formulation of claim 1 , wherein the formulation is a formulation that is non-toxic.
4. The formulation of claim 3 , wherein the formulation can be transported without significant degradation of the formulation, and the formulation is made by tank mixing, using a metering system to inject materials simultaneously, or mixing via a spray injection system.
5. The formulation of claim 1 , wherein the formulation comprises alkylene carbonate, which is ethylene carbonate, propylene carbonate, or mixtures thereof.
6. The formulation of claim 1 , wherein the formulation comprises polyol, which is glycerin, alkylene or poly(alkylene) glycols or mixtures thereof.
7. The formulation of claim 6 , wherein the formulation comprises polyol, which is an alkylene glycol selected from the group consisting of ethylene, propylene, butylene glycol, and mixtures thereof.
8. The formulation of claim 6 , wherein the polyol is glycerin.
9. The formulation of claim 1 , wherein the formulation comprises lactate, which is ethyl, propyl, or butyl lactate.
10. The formulation of claim 1 , wherein the N-(n-butyl)-thiophosphoric triamide (NBPT) is present in an amount that is 5-75 wt. % of the formulation.
11. The formulation of claim 1 , which has been diluted with water.
12. A fertilizer additive comprising N-(n-butyl) thiophosphoric triamide and R 1 S(O) R 2 wherein R 1 is methyl, ethyl, n-propyl, phenyl or benzyl and R 2 is methyl, ethyl, n-propyl, phenyl or benzyl, and one or more members selected from the group consisting of an ethylene or propylene carbonate or mixtures thereof, an alcohol or a polyol selected from the group consisting of alkylene and poly(alkylene) glycols, glycerin, and ethyl, propyl or butyl lactate wherein the fertilizer additive is prepared by dissolving the N-(n-butyl) thiophosphoric triamide into the R 1 S(O) R 2 and one or more members selected from the group consisting of the ethylene or propylene carbonate or mixtures thereof, the alcohol or the polyol selected from the group consisting of alkylene and poly(alkylene) glycols, glycerin, and the ethyl, propyl or butyl lactate.
13. The fertilizer additive of claim 12 , wherein the fertilizer additive comprises N-(n-butyl)-thiophosphoric triamide and dimethyl sulfoxide and one or more members selected from the group consisting of an ethylene or propylene carbonate or mixtures thereof, an alcohol or a polyol selected from the group consisting of alkylene and poly(alkylene) glycols, glycerin, and ethyl, propyl or butyl lactate.
14. The fertilizer additive of claim 13 , wherein the fertilizer comprises one or more polyalkylene glycols.
15. The fertilizer additive of claim 14 , wherein the one or more polyalkylene glycols are selected from the group consisting of polymethylene glycols, polyethylene glycols, polypropylene glycols, polybutylene glycols, and mixtures thereof.
16. A method of reducing the volatility of urea fertilizers comprising adding a composition to the urea fertilizers wherein the composition comprises N-(n-butyl)-thiophosphoric triamide and R 1 S(O) R 2 wherein R 1 is methyl, ethyl, n-propyl, phenyl or benzyl and R 2 is methyl, ethyl, n-propyl, phenyl or benzyl, and one or more members selected from the group consisting of an ethylene or propylene carbonate or mixtures thereof, an alcohol or a polyol selected from the group consisting of alkylene and poly(alkylene) glycols, glycerin, and ethyl, propyl or butyl lactate wherein the formulation is prepared by dissolving the N-(n-butyl) thiophosphoric triamide into the R 1 S(O) R 2 and wherein the composition further has the alcohol or the polyol selected from the group consisting of alkylene and poly(alkylene) glycols, glycerin, or the ethyl, propyl or butyl lactate added to the composition.
17. The method of claim 16 , wherein R 1 S(O) R 2 is dimethyl sulfoxide.
18. The method of claim 17 , wherein the composition comprises alkylene carbonate, which is ethylene carbonate, propylene carbonate, butylene carbonate or mixtures thereof.