IP Library Granted Patent US 8,986,940
Granted Patent B2
US 8,986,940 · App. 13/890,096 · Granted Mar 24, 2015

Detecting infection in reduced pressure wound treatment

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Quick Facts
Patent No.
US 8,986,940
App. No.
13/890,096
Granted
Mar 24, 2015
Kind
B2
Abstract

Provided is a method of detecting infection in a wound caused by an infecting organism at a wound site. Also provided is a system for detecting an infection in a wound at a wound site. Additionally, a porous pad comprising luciferase is provided.

Claims (17)

1. A system for detecting an infection at a wound site, the system comprising:

a source of reduced pressure;

a porous pad adapted to deliver the reduced pressure to the wound site;

a drape adapted to provide a substantially airtight cover over the porous pad and the wound site;

a conduit fluidly connecting the porous pad to the source of reduced pressure, wherein the conduit is configured to withdraw fluid from the wound site in response to the reduced pressure; and

a sensor adapted to identify a product of the infection or a component of an infecting organism in fluid withdrawn from the wound site;

whereby the presence of the product or the component indicates the presence of an infection in the wound.

2. The system of claim 1 , wherein the sensor comprises a photodetector and the porous pad further comprises luciferase and luciferin.

3. The system of claim 2 , wherein the luciferase is covalently bound to the porous pad.

4. The system of claim 1 , wherein the sensor comprises a compartment for placing a substrate comprising bound antibodies, the compartment adapted to allow fluid to flow onto the antibodies as fluid is drawn from the wound.

5. The system of claim 1 , wherein the sensor comprises a limulus amebocyte lysate.

6. The system of claim 1 , wherein the sensor comprises a microarray.

7. The system of claim 6 , wherein the microarray is in the reduced pressure source.

8. The system of claim 1 , further comprising a computer capable of recording data from the sensor.

9. A porous pad adapted for distributing reduced pressure to a wound site, wherein the pad comprises luciferase.

10. The porous pad of claim 9 , wherein the luciferase is covalently bound to the pad.

11. The porous pad of claim 9 , further comprising luciferin.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2024
From: 3M INNOVATIVE PROPERTIES COMPANY
To: SOLVENTUM INTELLECTUAL PROPERTIES COMPANY
Reel/Frame 066432/0376 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2023
From: KCI LICENSING, INC.
To: 3M INNOVATIVE PROPERTIES COMPANY
Reel/Frame 064790/0085 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Nov 7, 2019
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: KCI USA, INC.; KCI LICENSING, INC.
Reel/Frame 050966/0547 →
RELEASE OF SECURITY INTEREST REEL/FRAME 040098/0268 Recorded Feb 8, 2017
From: WILMINGTON TRUST
To: KCI USA, INC.
Reel/Frame 041666/0320 →
LIMITED THIRD LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Oct 7, 2016
From: KCI USA, INC.; LIFECELL CORPORATION; KCI LICENSING, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 040291/0237 →
SECOND LIEN SECURITY AGREEMENT Recorded Sep 21, 2016
From: KCI USA, INC.; LIFECELL CORPORATION; KCI LICENSING, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 040098/0268 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2014
From: MCNULTY, AMY; KILPADI, DEEPAK V.; HUTCHINSON, GEORGE; PRICE, NANCY
To: KCI LICENSING, INC.
Reel/Frame 034198/0432 →