Disposable container and mixing system comprising the container
View Patent ↗The present invention relates to a disposable container ( 100 ) comprising a side wall ( 2, 32 ), top ( 4 ) and bottom ( 6 ), wherein the side wall ( 2; 32 ) and the bottom ( 6 ) comprise a flexible material, wherein the side wall ( 2; 32 ), top ( 4 ) and bottom ( 6 ) are joined together to define the container ( 100 ) with an interior compartment ( 10 ) for keeping a fluid inside the container ( 100 ). The bottom ( 6 ) of the container ( 100 ) comprises at least one portion of rigid or semi-rigid material comprising a folding means ( 124; 224; 324; 324 ′) that enables folding of the bottom ( 6 ). Thus an easy way of folding the bottom of the container is provided.
1. A disposable container ( 100 ) for use in a bioreactor mixing system having an outer vessel for receiving the disposable container therein, the disposable container comprising:
a side wall ( 2 , 32 ) comprising a flexible material defining a side wall surface;
a top ( 4 ) comprising a flexible, rigid, or semi-rigid material defining a top surface;
a bottom ( 6 ) opposite the top ( 4 ) and comprising a flexible material defining a bottom surface that extends over the entire cross-section of the container; and
a folding means associated with the bottom surface; and
wherein the sidewall surface is joined to the top surface by a first seal extending along the entire periphery of the top surface, and wherein the sidewall surface is joined to the bottom surface by a second seal extending along the entire periphery of the bottom surface to define the container ( 100 ) with an interior compartment ( 10 ) for keeping a fluid inside the container ( 100 ) in a sterile manner;
wherein the folding means includes at least two rods of rigid or semi-rigid material forming a cross-shaped structure which enables the bottom ( 6 ) to be in a folded configuration or an unfolded configuration, wherein in the unfolded configuration, the at least two rods provide support for the bottom ( 6 );
wherein the disposable container further includes a support structure of rigid or semi-rigid material for supporting a mixing device placed in the interior compartment, wherein the support structure is connected to at least one of the rods at a crossing point of the at least two rods;
wherein the support structure is connected to the at least two rods on top of the at least two rods at a crossing point of the at least two rods; and
at least one of the rods is foldable upon itself such that a total height of the at least one rod, when folded upon itself, is greater than a height of the support structure.
2. The disposable container of claim 1 , wherein the rods ( 12 ; 120 ; 220 ; 322 ) are arranged perpendicular to each other.
3. The disposable container of claim 1 , wherein the folding means ( 124 ; 224 ; 324 ; 324 ′) is foldable only in one direction.
4. The disposable container of claim 3 , wherein the folding means ( 124 ; 224 ; 324 ; 324 ′) is at least one hinge.
5. The disposable container of claim 1 , wherein the flexible material is a plastic laminate.
6. The disposable container of claim 1 , wherein the side wall ( 2 ), top ( 4 ) and bottom ( 6 ) are joined together by means of a heat seal and/or an adhesive seal.
7. A mixing system comprising a vessel housing the disposable container ( 100 ) of claim 1 .
8. The disposable container of claim 1 , wherein the bottom ( 6 ) comprises port connectors ( 18 ).
9. The disposable container of claim 1 , which is adapted to hold a fluid in the interior compartment ( 10 ) in a sterile manner.
10. The disposable container of claim 1 , wherein:
the rods are each connected to the support structure via a hinge.
11. The disposable container of claim 1 , wherein:
the support structure is elliptical in shape.