IP Library › Patent Application 13921087
Patent Application
App. No. 13/921,087

COMBINATION NEISSERIAL COMPOSITIONS

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Quick Facts
Patent No.
US None
App. No.
13/921,087
Abstract

Compositions comprising a first biological molecule from a Neisseria bacterium and a second biological molecule from a Neisseria bacterium. The term “biological molecule” includes proteins and nucleic acids. Preferred Neisseria species are N. meningitidis and N. gonorrhoeae.

Claims (10)

1 . A composition comprising (i) a first substantially purified polypeptide comprising a fragment of SEQ ID NO: 3518, wherein the fragment of SEQ ID NO: 3518 includes 8 or more contiguous amino acids from SEQ ID NO: 3518; and (a) a second substantially purified polypeptide comprising a second fragment of SEQ ID NO: 3926, wherein the fragment of SEQ ID NO: 3926 includes 8 or more contiguous amino acids from SEQ ID NO: 3926.

2 . The composition of claim 1 wherein the fragment of SEQ ID NO: 3518 includes 14 or more contiguous amino acids from SEQ ID NO: 3518; and the fragment of SEQ ID NO: 3926 includes 14 or more contiguous amino acids from SEQ ID NO: 3926.

3 . The composition of claim 1 , wherein the first or second substantially purified polypeptide is a fusion protein.

4 . The composition of claim 3 , wherein the fusion protein comprises a GST protein or a HIS-tag.

5 . The composition of claim 2 , wherein the first or second substantially purified polypeptide is a fusion protein.

6 . The composition of claim 3 , wherein the first or second substantially purified polypeptide is a fusion protein.

7 . The composition of claim 1 , further comprising an adjuvant.

8 . The composition of claim 2 , further comprising an adjuvant.

9 . The composition of claim 7 , wherein the adjuvant comprises an aluminum salt.

10 . The composition of claim 8 , wherein the adjuvant comprises an aluminum salt.