Granted Patent
B2
US 9,365,602 · App. 13/925,981 · Granted Jun 14, 2016
Sodium glucose co-transporter inhibitors and methods of their use
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Abstract
Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.
Claims (2)
1. A method of treating or managing type 1 diabetes, which comprises administering to a patient in need thereof a therapeutically effective amount of (2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxy-benzyl)-phenyl]-6-methylsulfanyl-tetrahydro-pyran-3,4,5-triol:
or a pharmaceutically acceptable salt thereof.
Assignments (7)
RELEASE OF SECURITY INTEREST
Recorded May 5, 2026
From: OXFORD FINANCE LLC
To: LEXICON PHARMACEUTICALS, INC.; LEXICON PHARMACEUTICALS
Reel/Frame 075545/0601 →
SECURITY INTEREST
Recorded May 4, 2026
From: LEXICON PHARMACEUTICALS, INC.; LEXICON PHARMACEUTICALS (NEW JERSEY), INC.; LION ACQUISITION CORPORATION
To: HERCULES CAPITAL, INC., AS AGENT
Reel/Frame 075498/0899 →
SECURITY INTEREST
Recorded Mar 17, 2022
From: LEXICON PHARMACEUTICALS, INC.
To: OXFORD FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 059432/0709 →
RELEASE OF SECURITY INTEREST
Recorded Sep 14, 2020
From: BIOPHARMA CREDIT PLC
To: LEXICON PHARMACEUTICALS, INC.
Reel/Frame 053767/0445 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 26, 2018
From: HARRISON, BRYCE ALDEN; KIMBALL, SPENCER DAVID; MABON, ROSS; RAWLINS, DAVID BRENT
To: LEXICON PHARMACEUTICALS, INC.
Reel/Frame 045350/0424 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 26, 2018
From: GOODWIN, NICOLE C
To: LEXICON PHARMACEUTICALS, INC.
Reel/Frame 045350/0884 →
SECURITY INTEREST
Recorded Dec 20, 2017
From: LEXICON PHARMACEUTICALS, INC.
To: BIOPHARMA CREDIT PLC
Reel/Frame 044958/0377 →